Please use this identifier to cite or link to this item: http://repositorio.ufpa.br/jspui/handle/2011/10862
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Type: Artigo de Periódico
Issue Date: Aug-2018
Authors: PIRES, Carla Andréa Avelar
NORONHA, Marcos Antônio Neves
MONTEIRO, Julius Caesar Mendes Soares
COSTA, Albert Luiz Costa da
ABREU JÚNIOR, José Maria de Castro
metadata.dc.description.affiliation: UFPA/ICS
Title: Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital
Citation: PIRES, Carla Andréa Avelar et al. Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 93, n. 4, p. 524-528, ago 2018. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10862. Acesso em:.
Abstract: Background: Kaposi’s sarcoma (KS) is a rare neoplasm with indolent progression. Since 1981, the Kaposi’s sarcoma epidemic has increased as co-infection with HIV. Objectives: The study aimed to identify the clinical and demographic characteristics and therapeutic approaches in HIV/AIDS patients in a regional referral hospital. Methods: We analyzed the medical records of 51 patients with histopathological diagnosis of Kaposi’s sarcoma hospitalized at Hospital Universitário João de Barros Barreto (HUJBB) from 2004 to 2015. Results: The study sample consisted of individuals 15 to 44 years of age (80.4%), male (80.4%), single (86.3%), and residing in Greater Metropolitan Belém, Pará State, Brazil. The primary skin lesions identified at diagnosis were violaceous macules (45%) and violaceous papules (25%). Visceral involvement was seen in 62.7%, mainly affecting the stomach (75%). The most frequent treatment regimen was 2 NRTI + NNRTI, and 60.8% were referred to chemotherapy. Study limitations: We assumed that more patients had been admitted to hospital without histopathological confirmation or with pathology reports from other services, so that the current study probably underestimated the number of KS cases. Conclusion: Although the cutaneous manifestations in most of these patients were non-exuberant skin lesions like macules and papules, many already showed visceral involvement. Meticulous screening of these patients is thus mandatory, even if the skin lesions are subtle and localized.
Keywords: Acquired immunodeficiency syndrome
HIV
Human herpesvirus 8
Kaposi’s sarcoma
metadata.dc.relation.ispartof: Anais Brasileiros de Dermatologia
ISSN: 1806-4841
Country: Brasil
Publisher: Universidade Federal do Pará
Institution Acronym: UFPA
metadata.dc.rights: Acesso Aberto
metadata.dc.source.uri: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000400005&lng=pt&nrm=iso
metadata.dc.identifier.doi: http://dx.doi.org/10.1590/abd1806-4841.20186978
Appears in Collections:Artigos Científicos - ICS

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