Please use this identifier to cite or link to this item: http://repositorio.ufpa.br:8080/jspui/handle/2011/2426
Title: Relationship between plasma and red blood cell concentrations of quinine in Brazilian children with uncomplicated Plasmodium falciparummalaria on oral therapy
Other Titles: Relação entre as concentrações plasmáticas e eritrocitárias de quinina em crianças com malária por Plasmodium falciparum não complicada em terapia via oral
metadata.dc.creator: VIEIRA, José Luiz Fernandes
GOMES, Andreza de Lourdes Souza
BORGES, Larissa Maria Guimarães
GUIMARÃES, Erika Rodrigues
Keywords: Amazônia brasileira
Quinina
Malária falciparum
Cromatografia
Issue Date: Apr-2009
Citation: VIEIRA, José L. F. et al. Relationship between plasma and red blood cell concentrations of quinine in Brazilian children with uncomplicated Plasmodium falciparummalaria on oral therapy. Revista do Instituto de Medicina Tropical de São Paulo, São Paulo, v. 51, n. 2, p. 109-110, mar./abr. 2009. Disponível em: <http://www.scielo.br/pdf/rimtsp/v51n2/09.pdf>. Acesso em: 14 dez. 2011. http://dx.doi.org/10.1590/S0036-46652009000200009.
Abstract: We determined the relationship between plasma and red blood cell concentrations of quinine in children with uncomplicated falciparum malaria from an endemic area of Amazonian region. Quinine was determined by high performance liquid chromatography with ultraviolet detection. In the steady state the ratio between plasma and red blood cell quinine concentration was 1.89 ± 1.25 ranging from 1.05 to 2.34. This result demonstrated that quinine do not concentrate in red blood cell of Brazilian children and characterize the absence of interracial difference in this relationship.
URI: http://www.repositorio.ufpa.br:8080/jspui/handle/2011/2426
ISSN: 0036-4665
Appears in Collections:Artigos Científicos - FARM/ICS

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