Please use this identifier to cite or link to this item: http://repositorio.ufpa.br:8080/jspui/handle/2011/4858
Title: Estudo da ocorrência e perfil de suscetibilidade aos antimicrobianos de Staphylococcus aureus isolados de pacientes e profissionais de saúde na Unidade de Terapia Intensiva de hospital público de Rio Branco-AC
metadata.dc.creator: LAVIOLA GARCÊZ, Poliana Torres
metadata.dc.contributor.advisor1: LOUREIRO, Edvaldo Carlos Brito
Keywords: Infecção hospitalar
Unidades de terapia intensiva
Hospitais públicos
Staphylococcus aureus
Fatores de risco
Hospital de Urgência e Emergência de Rio Branco
Rio Branco -AC
Acre - Estado
Amazônia brasileira
Issue Date: 7-Feb-2011
Publisher: Universidade Federal do Pará
Citation: LAVIOLA GARCÊZ, Poliana Torres. Estudo da ocorrência e perfil de suscetibilidade aos antimicrobianos de Staphylococcus aureus isolados de pacientes e profissionais de saúde na Unidade de Terapia Intensiva de hospital público de Rio Branco-AC. 2011. 101 f. Dissertação (Mestrado) – Universidade Federal do Pará, Instituto de Ciências Biológicas, Belém, 2011. Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários.
Abstract: The nosocomial infection is a serious public health problem worldwide, mainly in patients admitted to the Intensive Care Unit, which are subject to greater risk due to the severity of clinical symptoms, constant use of broad spectrum antibiotics and frequency of use of invasive procedures. Staphylococcus aureus is a major pathogen that colonizes healthy individuals and is also responsible for infections in hospitalized patients. This study aimed to identify the resistance profile, main sites affected by infection and possible risk factors associated with infection or colonization by S. aureus isolated from patients and healthcare professionals from the Intensive Care Unit of Hospital Emergency and Emergency, Rio Branco (HUERB) – Acre. We developed a cross-sectional study, conducted between January to August 2009. To search for carriers, biological samples were collected from microbiota of patients and professionals and professionals hand washing. For a survey of cases of patients with nosocomial infection were collected biological samples from sites suspected of being affected, 72 hours from the date of admission until discharge, transfer or death. Of the 62 patients enrolled in the study, 19.3% were carriers and 6.4% developed nosocomial infections by S. aureus, and 35 professionals, 28.6% were carriers of S. aureus. It was the second most bacterial species isolated from patients, and was the fifth most isolated from cases of nosocomial infection. There was no statistical evidence for the variable state of coma, use of invasive procedures and state of carrier patient are considered risk factors for acquiring nosocomial S. aureus in this study. The anatomical sites affected by IH by S. aureus were the respiratory tract ( n=2), followed by blood (n=1). The sample catheter tip was responsible for one insulated. One (1.6%) patient developed IH by MRSA, and 5 (8,1%) patients and 2 ( 5.7%) professionals were MRSA carriers, low occurrence as it relates to the results of the rest of Brazil and world. We also emphasize the incidence of MRSA over MSSA and low antomicrobial resistance of MRSA demonstrating that the UTI-HUERB, the IH S. aureus does not constitute a public health problem. There were no isolates of S. aureus resistant to vancomicina, wich can be considered a therapeutic option for cases of IH by MRSA. It is worth emphasizing the importance of this study in Acre State, for being the first of its kind in the UTI, involving S. aureus and MRSA.
URI: http://repositorio.ufpa.br/jspui/handle/2011/4858
Appears in Collections:Dissertações em Biologia de Agentes Infecciosos e Parasitários (Mestrado) - PPGBAIP/ICB

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