Please use this identifier to cite or link to this item: http://repositorio.ufpa.br:8080/jspui/handle/2011/6335
Full metadata record
DC FieldValueLanguage
dc.creatorBOTELHO, Nara Macedo-
dc.creatorSILVEIRA, Edvaldo Lima-
dc.creatorLOPES, Letícia Nobre-
dc.creatorSANTOS, Felipe Augusto Folha-
dc.creatorTEIXEIRA, Renan Kleber Costa-
dc.creatorSILVA, Thaís Travassos da-
dc.date.accessioned2015-02-24T15:28:27Z-
dc.date.available2015-02-24T15:28:27Z-
dc.date.issued2014-08-
dc.identifier.citationBOTELHO, Nara Macedo et al. Copaiba oil effect under different pathways in mice subjected to sepsis. Acta Cirúrgica Brasileira, São Paulo, v. 29, n. 8, p. 528-531, Aug. 2014. DOI: http://dx.doi.org/10.1590/S0102-86502014000800008. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/6335. Acesso em:.pt_BR
dc.identifier.issn1678-2674-
dc.identifier.urihttp://repositorio.ufpa.br/jspui/handle/2011/6335-
dc.description.abstractPURPOSE: To evaluate the effects of copaiba oil administered by different routes on survival of mices subjected to cecal ligation and puncture. METHODS: Thirty two mice were distributed into four study groups (N=8): Sham group: normal standard animals; Control group: submitted a cecal ligation and puncture (CLP); Gavage group: submitted a CLP, and treat with copaiba oil by gavage; and Subcutaneous group: submitted a CLP, and treat with copaiba oil by subcutaneous injection. After the death of the histological analysis were performed. The Kaplan-Meier curves of surviving time were realized. RESULTS: All animals that received copaiba, regardless of the route used, survived longer when compared to the control group (p<0.0001), whereas the survival time ranged from 20 hours for the control group up to 32 hours for the animals of gavage group and 52 for subcutaneous group. The animals that received gavage copaiba lived about and about 20 hours unless the subcutaneous group (p=0.0042). There was no statistical difference when compared the intensity of inflammatory response (p>0.05). CONCLUSION: Prophylactic subcutaneous administration of copaiba in mice subjected to severe sepsis by cecal ligation and puncture, resulted in a survival time higher than non-use or use of this oil by gavage.en
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico-
dc.language.isoengpt_BR
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia-
dc.relation.ispartofActa Cirúrgica Brasileira-
dc.rightsAcesso Abertopt_BR
dc.source.urihttp://ref.scielo.org/fdkky3-
dc.subjectPlantas medicinaispt_BR
dc.subjectÓleo de copaíbapt_BR
dc.subjectDoenças peritoneaispt_BR
dc.subjectRato como animal de laboratóriopt_BR
dc.subjectBalsamsen
dc.subjectPeritoneal diseasesen
dc.subjectLigationen
dc.subjectMiceen
dc.titleCopaiba oil effect under different pathways in mice subjected to sepsisen
dc.typeArtigo de Periódicopt_BR
dc.publisher.countryBrasil-
dc.publisher.initialsSOBRADPEC-
dc.creator.Latteshttp://lattes.cnpq.br/5088569652644480-
dc.creator.Latteshttp://lattes.cnpq.br/7986498092293019-
dc.creator.Latteshttp://lattes.cnpq.br/4734095669999459-
dc.creator.Latteshttp://lattes.cnpq.br/3144112004152037-
dc.creator.Latteshttp://lattes.cnpq.br/5246017785240786-
dc.creator.Latteshttp://lattes.cnpq.br/7391648610716249-
dc.citation.volume29-
dc.citation.issue8-
dc.citation.spage528-
dc.citation.epage531-
dc.identifier.doihttp://dx.doi.org/10.1590/S0102-86502014000800008-
dc.description.affiliationSILVEIRA, E. L. Universidade Federal do Pará-
Appears in Collections:Artigos Científicos - ICB

Files in This Item:
File Description SizeFormat 
Article_CopaibaOilEffect.pdf279,11 kBAdobe PDFView/Open


This item is licensed under a Creative Commons License Creative Commons