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metadata.dc.type: Artigo de Periódico
Issue Date: Jun-2011
metadata.dc.creator: OLIVEIRA, Caio Maximino de
Title: Modulation of nociceptive-like behavior in zebrafish (Danio rerio) by environmental stressors
Citation: MAXIMINO, Caio. Modulation of nociceptive-like behavior in zebrafish (Danio rerio) by environmental stressors. Psychology & Neuroscience, Rio de Janeiro, v. 4, n. 1, p. 149-155, jun. 2011. Disponível em: <>. Acesso em: 27 fev. 2012. <>.
Abstract: Zebrafish have been demonstrated to react consistently to noxious chemical stimuli and present reliable phenotypes of stress, fear, and anxiety. In this article, we describe the modulation of nociceptive-like responses of zebrafish to fear-, stress-, and anxiety-eliciting situations. Animals were exposed to an alarm substance, confinement stress, or a novel environment before being injected with 1% acetic acid in the tail. The alarm substance and confinement stress reduced the display of erratic movements and tail-beating behavior elicited by acetic acid. The novelty of the environment, in contrast, increased the frequency of tail-beating behavior. The results suggest that descending modulatory control of nociception exists in zebrafish, with apparent fear- and stress-induced analgesia and anxiety-induced hyperalgesia.
Keywords: Teleósteos
Comportamento animal
Farmacologia experimental
Peixe zebra
ISSN: 1983-3288
metadata.dc.rights: Acesso Aberto
Appears in Collections:Artigos Científicos - ICB

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