Please use this identifier to cite or link to this item: http://10.7.2.42:8080/jspui/handle/2011/9099
Title: Análise da variabilidade da frequência cardíaca em pacientes hansenianos: análise linear, simbólica e de complexidade
Authors: SOUZA, Givago da Silva
http://lattes.cnpq.br/5705421011644718
Keywords: Doença infectocontagiosa
Cardiologia
Hanseníase multibacilar
Frequência cardíaca
Disfunção autonômica cardíaca
Issue Date: 2014
Publisher: Universidade Federal do Pará
Citation: SANTOS, Marcio Clementino de Souza. Análise da variabilidade da frequência cardíaca em pacientes hansenianos: análise linear, simbólica e de complexidade. 2014. 104 f. Tese (Doutorado) – Universidade Federal do Pará, Núcleo de Medicina Tropical, Belém, 2014. Programa de Pós-Graduação em Doenças Tropicais.
Abstract: Objective: the purpose of this study was to evaluate the heart rate variability (HRV) in patients with multibacillary leprosy clinic history, from dynamic linear and nonlinear analysis. Materials and methods: this is an experimental not randomized, quantitative study with 42 volunteers of both genres, divided into 2 groups of 21. The first group (LG), with 21 leprosy patients, aged 39.14 ±10.58 years, and the second group (CG), with 21 healthy subjects aged 36.24 ± 12.64 years. HR capture was performed by a heart monitor Polar RS800 CX, for a period of 15 min in the supine and 15 min in a sitting position. Analysis of HRV was performed by frequency domain from high frequency spectral indices (HFun), low frequency (LFun) in standard units and reason BF/AF. The nonlinear analysis of HRV was calculated by symbolic analysis (0V indexes%, 1V%, wholesale% and 2ULV%) shannon entropy (SE) and normalized complexity index (NCI). Results: In the spectral analysis of HRV LG presented higher values (p<0.05) of LFun and smaller values (p<0.05) of HFun compared to CG, on bench press position. Both groups showed higher values (p<0.05) of HFun and smaller values (p<0.05) of LFun in supine position in relation to a sitting position. There was no change of reason LF/HF in the comparison between groups and between positions evaluated. Symbolic analysis LG presented higher values (p<0.05) of 0V index% and smaller values (p<0.05) of the 2LV% and 2ULV% index in relation to the CG, in both positions evaluated. The index 1V% was higher (p<0.05) in the LG in relation to the CG just comparing to a sitting position. The CG presented minors values (p<0.05) of 0V index% and higher values (p<0.05) 2ULV% index supine position in relation to a sitting position. The LG presented higher values (p<0.05) 2ULV% index supine position in relation to a sitting position. On the complexity analysis LG presented minors values (p<0.05) of SE and ICN with respect to CG, on bench press position. There were no differences between the groups in SE and NCI analyzed in a sitting position. The CG presented higher values (p<0.05) of ES and ICN on bench press position in relation to a sitting position. Conclusion: The LG present greater sympathetic modulation and less vagal modulation in relation to the CG, indicating less HRV and cardiac modulation with low complexity. In response to postural change, both groups showed increased vagal modulation on position supine, evidencing greater HRV in this condition. Analysis of HRV by linear and non-linear dynamics proved to be a sensitive method and promising for investigation of autonomic dysfunction in patients with multibacillary leprosy.
URI: http://repositorio.ufpa.br/jspui/handle/2011/9099
Appears in Collections:Teses em Doenças Tropicais (Doutorado) - PPGDT/NMT

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