Navegando por Autor "FERREIRA, Izabel Cristina Piloto"

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Active polyketides isolated from Penicillium herquei
(2013-09) MARINHO, Andrey Moacir do Rosário; MARINHO, Patrícia Santana Barbosa; SANTOS, Lourivaldo da Silva; RODRIGUES FILHO, Edson; FERREIRA, Izabel Cristina Piloto
In this work we are reporting the isolation by classical methods of chromatography of six polyketides from Penicillium herquei. The compounds citreorosein ( 1) , emodin ( 2) , janthinone ( 3) , citrinin ( 4) , citrinin H1 ( 5) and dicitrinol ( 6) were identified by spectral methods of 1D and 2D NMR and MS. Compounds 1, 2 and 3 were tested against promastigotes forms of Leishmania brasiliensis and 1 and 2 were also assayed against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis and showed good activity.
Acesso aberto (Open Access)
Policetídeos isolados de Penicillium herquei
(2011) MARINHO, Anderson Nonato do Rosario; MARINHO, Patrícia Santana Barbosa; RODRIGUES FILHO, Edson; FERREIRA, Izabel Cristina Piloto
In this work we are reporting the isolation of polyketides citreoserine (1), emodin (2), janthinone (3), dihydrocitrinone (4) and citrinin H-1 (5). The compounds were isolated by chromatographic procedures and identified by spectral methods of NMR 1D and 2D and MS. The compounds 1, 2 and 3 were tested against promastigotes of Leishmania brasiliensis.