Navegando por Autor "FREITAS, Andrei Silva"

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Hepatitis B and C virus infection among Brazilian Amazon riparians
(2011-10) OLIVEIRA, Claudia Suellen Ferro de; SILVA, Adenielson Vilar e; SANTOS, Kemper Nunes dos; FECURY, Amanda Alves; ALMEIDA, Marcella Kelly Costa de; FERNANDES, Adriana Prado; COSTA, Carlos Araújo da; FREITAS, Andrei Silva; CORVELO, Tereza Cristina de Oliveira; MARTINS, Luisa Caricio
INTRODUCTION: Viral hepatitis is a major public health concern in Brazil. There are few past studies on this issue, especially among riparian communities. This study aims at determining the seroprevalence of viral hepatitis B and C in the riparian community of Pacuí Island, within the Cametá municipality of Pará State, Brazil. Moreover, this study aims to investigate the principal risk factors that this community is exposed to. METHODS: The current study has accessed blood samples from 181 volunteers who have answered an epidemiological questionnaire. Analyses on serological markers have been tested with commercial ELISA kits for detecting HBsAg, total anti-HBc, anti-HBs, and anti-HCV. Within seroreactive patients for HCV, RT-PCR and line probe assay have been performed to identify the viral genotype. RESULTS: In the serological marker analysis for hepatitis B, no reactivity for HBsAg, rate of 1.1% for total anti-HBc, and rate of 19.3% for anti-HBs have been observed. On hepatitis C, 8.8% seroprevalence has been found, in which 62.5% have gotten viral RNA. Among the risk factors studied, the following have been highlighted: non-use of condoms, sharing of cutting instruments, use of illicit drugs, and reports of family disease with HBV or HCV. CONCLUSIONS: The vaccination coverage against HBV is low, and the high prevalence of HCV within this community has been observed.
Acesso aberto (Open Access)
Prevalência e fatores de risco para a Hepatite viral B em pacientes submetidos a hemodiálise na cidade de Belém/PA – Brasil
(Universidade Federal do Pará, 2014) FREITAS, Andrei Silva; MARTINS, Luisa Caricio; http://lattes.cnpq.br/1799493244439769
Hepatitis B virus (HBV) infection is a major worldwide health problem. Recent studies have reported that patients with chronic kdney desease on hemodialysis are at high risk of acquiring HBV. The research was conducted in three Hemodialysis Centers in the city of Belém, Pará , Northern Brazil . The objective of this study was to describe the prevelence of HBV infection associated risk factors. A total of 298 patients were interviewed in three hemodialysis centers. Serum samples were screened for HBV serological markers by ELISA ( Enzyme-linked Immunosorbent Assay) . A percentage of 26.85 % (80/ 298) of individuals who have come into contact with HBV ( 23/298 HBsAg reagent and 67/298 reagent for anti - HBc Total) was observed . Individuals who have multiple sexual partners , who received blood transfusion , sharing nail clippers and those on hemodialysis for more than five years have a higher risk for acquiring HBV.