Navegando por Autor "MELLO, Wyller Alencar de"

Agora exibindo 1 - 2 de 2

Acesso aberto (Open Access)
Inquérito soroepidemiológico para os vírus influenza em Belém, Pará, Brasil, 1992-1993
(1997-03) SANTOS, Domingos Ezenildo Matos dos; CARDIAS, Cláudia Alessandra da Silva; MELLO, Wyller Alencar de
A seroepidemiological study was carried out from 1992 to 1993 to estimate the prevalence of antibody to prevailing influenza virus strains circulating among patients attending the IEC Virology Laboratory in Belem, Northern Brazil. A total of 179 (11%) of serum samples were obtained during the post-epidemic period and processed by the hemagglutination inhibition test against the A/Taiwan/1/86 (H1N1), A/Beijing/353/89 (H3N2), and B/Yamagata/16/88 types of influenza virus. The serological results indicate circulation of viruses antigenically related to all three strains during the two-year study period. In 1992, the overall prevalence rates of HI antibodies to H1N1 and H3N2 were 84% and 56%, respectively. Presence of antibodies to both strains was detected in all age groups, suggesting intense viral activity that year. Antibodies to influenza B were detected at lower levels in all patients during this period. Similar prevalence to the H1N1 virus was noted in 1993, indicating that this strain occurred in both years. However, an increase in prevalence rates for the H3N2 virus was seen in 1993, suggesting that this strain (or a related virus) circulated intensively during this year. Influenza B activity also increased in 1993, causing infection mainly among young adults.
Acesso aberto (Open Access)
Papilomavírus humano associado a lesões de cérvice uterina
(1999-06) CAVALCANTE, Vânia Lúcia Noronha; MELLO, Wyller Alencar de; VILLA, Luísa Lina; BRITO, Arival Cardoso de; MACEDO, Roberto Cavalleiro de; BISI, Fátima; SASSAMOTO, Kyio; MONTEIRO, Talita Antonia Furtado; LINHARES, Alexandre da Costa
It was studied the prevalence of human papillomavirus (HPV) among 228 women with lesions of uterine cervix attending the Ofir Loiola Institute, in Belem, Para, from March 1992 to May 1996. Histopathological examination was performed with all cervical biopsy samples obtained from these patients. In addition, specimens were analysed by both polimerase chain reaction and dot-blot hybridization to detect HPV DNA. The patients were assigned to three groups, according to the diagnosis made by histopathology, as follows: A, including 155 women suffering from invasive epidermoid carcinoma or adenocarcinoma; B, 54 patients having either cervical intraepithelial neoplasia grade II or III; and C, involving 19 women with chronic cervicitis. The prevalence rates of HPV in groups A, B and C were 70.3%, 63% and 36.8% respectively. HPV 16 accounted for 60.4% and 54.5% of types identified in groups A and B, respectively. Altogether HPV types 16, 18 and 33 were detected in 71.4% of positive patients belonging to group C.