Navegando por Autor "MIRANDA, Mario Fernando Ribeiro de"

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Comparison between histopathologic features of leprosy in reaction lesions in HIV coinfected and non-coinfected patients
(2015-02) PIRES, Carla Andréa Avelar; MIRANDA, Mario Fernando Ribeiro de; BITTENCOURT, Maraya de Jesus Semblano; BRITO, Arival Cardoso de; XAVIER, Marília Brasil
BACKGROUND: Leprosy and HIV are diseases that have a major impact on public health in Brazil. Patients coinfected with both diseases, appear to be at higher risk to develop leprosy reactions. OBJECTIVE: The aim of this study is to describe the histopathological aspects of cutaneous lesions during reactional states in a group of patients with HIV-leprosy coinfection, compared to patients with leprosy, without coinfection. METHODS: Two groups were established: group 1 comprised of 40 patients coinfected with HIV-leprosy; group 2, comprised of 107 patients with leprosy only. Patients presenting reactional states of leprosy had their lesions biopsied and comparatively evaluated. RESULTS: Reversal reaction was the most frequent feature in both groups, with dermis edema as the most common histopathological finding. Giant cells were seen in all group 1 histopathological examinations. Dermis edema was the most common finding in patients with erythema nodosum leprosum. CONCLUSION: Few histopathological differences were found in both groups, with reversal reaction as the most significant one, although this fact should be analyzed considering the predominant BT clinical form in the coinfected group and BB form in the group without HIV. Larger prospective studies in patients with HIV-leprosy coinfection are needed to confirm and broaden these results.
Acesso aberto (Open Access)
Dermatofibroma in a black tattoo: report of a case
(Universidade Federal do Pará, 2012-08-01) BITTENCOURT, Maraya de Jesus Semblano; MIRANDA, Mario Fernando Ribeiro de; PARIJÓS, Amanda Magno de; FONSECA, Diana Mendes da; JAMBO, Diego Augusto Aiezza; MESQUITA, Letícia Brito
Tattooing has been associated with a variety of complications including inflammatory and granulomatous reactions, transmission of infections, and neoplasms. We report a case of a 24-year-old male who presented with a 2-month history of an erythematous nodule involving a newly made tattoo on the right leg. An excisional biopsy was performed and the histopathological evaluation was consistent with dermatofibroma. Only three cases of dermatofibroma associated with tatooing were reported in litetature. We report an additional case and review the literature regarding cutaneous reactions to tattoos.
Acesso aberto (Open Access)
Leucodermia sifilítica: expressão rara do secundarismo diagnosticada por exame histopatológico
(Universidade Federal do Pará, 2010-08) MIRANDA, Mario Fernando Ribeiro de; BITTENCOURT, Maraya de Jesus Semblano; LOPES, Igor da Costa; CUMINO, Shirley do Socorro Magalhães
Biopsies are occasionally necessary to confirm the diagnosis of secondary-stage syphilis, currently achieved by clinico-serological correlation. However, histopathologic examination may offer clues that can lead to the diagnosis of the disease in previously unsuspected or unusual cases. We report the case of a 35-year-old male patient with vitiligo-like lesions for two years, whose diagnosis of syphilis was suggested only after histopathologic examination. Some microscopic aspects observed are discussed and compared to data from the literature.