Navegando por Autor "OLIVEIRA, Roseane Borner de"

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Acesso aberto (Open Access)
Aspectos epidemiológicos e clínico-patológicos comparados da intoxicação por Arrabidaea bilabiata (Bignoniaceae) em búfalos e bovinos
(2004-06) TOKARNIA, Carlos Maria Antônio Hubinger; BARBOSA NETO, José Diomedes; OLIVEIRA, Carlos Magno Chaves; BRITO, Marilene de Farias; OLIVEIRA, Roseane Borner de; BARBAS, Luiz André Luz
Experiments showed that the clinical and pathological pictures were essentially the same, but the buffalo was at least twice more resistant than the bovine to the toxic effect of Arrabidaea bilabiata (Sprague) Sandw. It was also shown that the young leaves are twice (October, end of the dry season) or one and a half (May, end of the rainy season) more toxic than the mature leaves, and that the plant is more toxic in October. These data indicate that the smaller incidence of poisoning by plants of the group that causes sudden death in buffaloes in the Amazon Region is, in part, due to the greater resistance of this animal species to the toxic action of the plant. Also important seems to be the coincidence of the preferential habitat of the buffalo (flooded areas) with the habitat of A. bilabiata, less toxic than Palicourea marcgravii St.Hil. which is a plant of the non-flooded areas, the preferential habitat of cattle.
Acesso aberto (Open Access)
Neurodegeneração crônica em modelo murino: ensaios comportamentais e neuropatológicos na doença prion em fêmeas adultas de camundongos albinos suíços
(Universidade Federal do Pará, 2009-04-30) OLIVEIRA, Roseane Borner de; DINIZ, Cristovam Wanderley Picanço; http://lattes.cnpq.br/2014918752636286
In the present report we described behavioral and neuropathological changes induced by ME7 prion agent inoculated into CA1 of the albino Swiss mice and confirmed previous descriptions in the murine model of prion disease C57Bl6J with two exceptions: 1) septal region present higher level of microglial activation and reactive astrocytosis 2) disease progression (from inoculation to death) is 4 weeks longer and on average, early behavioral changes start correspondently 4 weeks later in albino Swiss mice. Neuronal counts did not reveal any significant changes between the experimental groups. Comparative analysis of activated microglia and perineuronal nets by optical fractionators revealed significant differences between 15 and 18 weeks: the microglial total number increased in this period of time whereas perineuronal nets decreased (t test, two-tailed analysis p<0.05) Cluster and discriminant subsequent analysis applied to behavioral studies revealed that burrowing activity distinguished the occurrence of two subgroups with differential sensitivity to the ME7 agent: one group (40% of the subjects) where the disease progression is faster and the terminal stage is reached in 22 weeks and another one (60%) with slower progression and terminal stage at 26 weeks post-inoculation. The results are important for comparative studies of the immunoneuropathology of chronic neurodegenerative disorders in general and for prion disease itself.