Navegando por Autor "SANTIAGO, Mittermayer Barreto"

Agora exibindo 1 - 3 de 3

Acesso aberto (Open Access)
3º Consenso Brasileiro para pesquisa de autoanticorpos em células HEp-2 (FAN): recomendações para padronização do ensaio de pesquisa de autoanticorpos em células HEp-2, controle de qualidade e associações clínicas
(2009-04) DELLAVANCE, Alessandra; GABRIEL JÚNIOR, Alexandre; NUCCITELLI, Barbara; TALIBERTI, Ben-Hur Braga; VON MÜHLEN, Carlos Alberto; BICHARA, Carlos David Araújo; SANTOS, Cláudio Henrique Ramos dos; BUENO, Cleonice; YANO, Cristiane Martinez; MANGUEIRA, Cristóvão Luis Pitangueira; CARVALHO, Darlene Gonçalves; CARDOSO, Elizângela; BONFÁ, Eloísa Silva Dutra de Oliveira; ARAÚJO, Flávia Ikeda e; RASSI, Gustavo Gabriel; MUNDIM, Hugo Mendonça; BENDET, Izidro; RÊGO, Jozelia; VIEIRA, Lisiane Maria Enriconi dos Anjos; ANDRADE, Luis Eduardo Coelho; BARBOSA, Maria Ordália Ferro; SUGIYAMA, Mitiko; SANTIAGO, Mittermayer Barreto; BARRETO, Natasha Slhessarenko Fraife; SILVA, Nilzio Antônio da; FRANCESCANTONIO, Paulo Luiz Carvalho; JARACH, Renata; SUDA, Roberto; LEVY, Roger Abramino; SAMPAIO, Silvia Oliveira; NEVES, Suzane Pretti Figueiredo; CRUVINEL, Wilson de Melo; SANTOS, Wilton Silva dos; NÓBREGA, Yanna Karla de Medeiros
The Third Brazilian Consensus for autoantibodies Screening in HEp-2 cells had as purpose the evaluation of difficulties in the accomplishment of the 2nd Consensus recommendations that took place in the year of 2002, the discussion of strategies for quality control of the assay and the promotion of an update of the clinical associations of the several immunofluorescent patterns. METHODS:Several ANA experts from university centers and private laboratories in different areas in Brazil joined the workshop in Goiânia on 2008 April 13 and 14 with the purpose of discussing and approving the recommendations for standardization, interpretation and use of the test by physicians. Commercial representatives of different ANA slide brands were also invited as listeners to the workshop. RESULTS AND CONCLUSIONS: The 3rd Consensus emphasized the need for quality control in indirect immunofluorescent since there is a considerable heterogeneity of available microscopes and reagents. It also promoted adaptations in the previously approved terminology used to classify the different patterns and finally updated the clinical associations of the several patterns with the purpose of providing guidance for interpretation of the assay by clinical pathologists and assistant physicians.
Acesso aberto (Open Access)
Artrite enteropática no Brasil: dados do registro brasileiro de espondiloartrites
(Universidade Federal do Pará, 2013-12) RESENDE, Gustavo Gomes; LANNA, Cristina Costa Duarte; BERTOLUZZO, Adriana Bruscato; GONÇALVES, Celio Roberto; XIMENES, Antonio Carlos; BERTOLO, Manoel Barros; KEISERMAN, Mauro Waldemar; MENIN, Rita de Cássia; SKARE, Thelma Larocca; CARNEIRO, Sueli Coelho da Silva; AZEVEDO, Valderílio Feijó; VIEIRA, Walber Pinto; BIANCHI, Washington Alves; BONFIGLIOLI, Rubens; CAMPANHOLO, Cristiano Barbosa; CARVALHO, Hellen Mary da Silveira de; COSTA, Izaias Pereira da; DUARTE, Angela Luzia Branco Pinto; KOHEM, Charles Lubianca; MEIRELLES, Eduardo de Souza; PEREIRA, Ivânio Alves; PINHEIRO, Marcelo de Medeiros; POLITO, Elizandra Tomazela Laurenti; ROCHA, Francisco Airton Castro da; SANTIAGO, Mittermayer Barreto; CUNHA, Maria de Fátima Lobato da; VALIM, Valéria; BARROS, Percival Degrava Sampaio; RIBEIRO, Sandra Lúcia Euzébio; SILVA, José Antonio Braga da; ALBUQUERQUE, Elisa N.; LEITE, Nocy; LIMA, Sonia A. L.
Inflammatory bowel diseases (Crohn’s disease and ulcerative rectocolitis) have extraintestinal manifestations 25% of the patients, with the most common one being the enteropathic arthritis. Methods: Prospective, observational, multicenter study with patients from 29 reference centers participating in the Brazilian Registry of Spondyloarthritis (RBE), which incorporates the RESPONDIA (Ibero-American Registry of Spondyloarthritis) group. Demographic and clinical data were collected from 1472 patients and standardized questionnaires for the assessment of axial mobility, quality of life, enthesitic involvement, disease activity and functional capacity were applied. Laboratory and radiographic examinations were performed. The aim of this study is to compare the clinical, epidemiological, genetic, imaging, treatment and prognosis characteristics of patients with enteropathic arthritis with other types of spondyloarthritis in a large Brazilian cohort. Results: A total of 3.2% of patients were classified as having enteroarthritis, 2.5% had spondylitis and 0.7%, arthritis (peripheral predominance). The subgroup of individuals with enteroarthritis had a higher prevalence in women (P < 0.001), lower incidence of inflammatory axial pain (P < 0.001) and enthesitis (P = 0.004). HLA-B27 was less frequent in the group with enteroarthritis (P = 0.001), even when considering only those with the pure axial form. There was a lower prevalence of radiographic sacroiliitis (P = 0.009) and lower radiographic score (BASRI) (P = 0.006) when compared to patients with other types of spondyloarthritis. They also used more corticosteroids (P < 0.001) and sulfasalazine (P < 0.001) and less nonsteroidal anti-inflammatory drugs (P < 0.001) and methotrexate (P = 0.001). Conclusion: There were differences between patients with enteroarthritis and other types of spondyloarthritis, especially higher prevalence of females, lower frequency of HLA-B27, associated with less severe axial involvement.
Acesso aberto (Open Access)
III Consenso Brasileiro para Pesquisa de Autoanticorpos em Células HEp-2: perspectiva histórica, controle de qualidade e associações clínicas
(2009-06) FRANCESCANTONIO, Paulo Luiz Carvalho; ANDRADE, Luis Eduardo Coelho; CRUVINEL, Wilson de Melo; ARAÚJO, Flávia Ikeda e; DELLAVANCE, Alessandra; GABRIEL JÚNIOR, Alexandre; NUCCITELLI, Barbara; TALIBERTI, Ben-Hur Braga; VON MÜHLEN, Carlos Alberto; BICHARA, Carlos David Araújo; SANTOS, Cláudio Henrique Ramos dos; BUENO, Cleonice; YANO, Cristiane Martinez; MANGUEIRA, Cristóvão Luis Pitangueira; CARVALHO, Darlene Gonçalves; CARDOSO, Elizângela; BONFÁ, Eloísa Silva Dutra de Oliveira; RASSI, Gustavo Gabriel; MUNDIM, Hugo Mendonça; BENDET, Izidro; RÊGO, Jozelia; VIEIRA, Lisiane Maria Enriconi dos Anjos; BARBOSA, Maria Ordália Ferro; SUGIYAMA, Mitiko; SANTIAGO, Mittermayer Barreto; BARRETO, Natasha Slhessarenko Fraife; SILVA, Nilzio Antônio da; JARACH, Renata; SUDA, Roberto; LEVY, Roger Abramino; SAMPAIO, Silvia Oliveira; NEVES, Suzane Pretti Figueiredo; SANTOS, Wilton Silva dos; NÓBREGA, Yanna Karla de Medeiros
OBJECTIVE: The Third Brazilian Consensus for Autoantibodies Screening in HEp-2 Cells (ANA) had as purpose the evaluation of difficulties in the accomplishment of the 2nd Consensus recommendations that took place in the year of 2002, the discussion of strategies for quality control of the assay and the discussion of an update of the clinical associations of the several immunofluorescent patterns. METHODS: Several ANA experts from university centers and private laboratories in different areas in Brazil joined the workshop in Goiânia on 2007 April 13 and 14 with the purpose of discussing and approving the recommendations for standardization, interpretation and use of the test by physicians. Commercial representatives of different ANA slide brands were also invited as listeners to the workshop. RESULTS AND CONCLUSION: The 3rd ANA Consensus emphasized the need for quality control in indirect immunofluorescent assays since there is a considerable heterogeneity of available microscopes and reagents. It also promoted adaptations in the previously approved terminology used to classify the different patterns and finally updated the clinical associations of the several patterns with the purpose of providing guidance for interpretation of the assay by clinical pathologists and assistant physicians.