Navegando por Autor "SANTOS, Wallace Raimundo Araujo dos"

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Factors associated with overweight and central adiposity in urban workers covered by the Workers Food Program of the Brazilian Amazon Region
(Universidade Federal do Pará, 2010-09) ARAUJO, Marilia de Souza; COSTA, Teresa Helena Macedo da; SCHMITZ, Bethsáida de Abreu Soares; MACHADO, Liliane Maria Messias; SANTOS, Wallace Raimundo Araujo dos
OBJECTIVE: To investigate factors associated with overweight and abdominal obesity in male and female workers. METHODS: This is a cross-sectional population-based study. A representative sample of 1,054 workers ranging from 18 to 74 years of age, selected among individuals covered by the Workers´ Food Program living in the Metropolitan region of Belém, Northern Brazil. Health-related behavior and anthropometry were assessed. Fasting blood samples were collected. RESULTS: Overweight prevalence was 38.0% among women and 50.4% among men. Among overweight subjects, there were 6.1% obese women and 10.7% obese men. Multivariate analysis was used to identify social behavior and clinical-biochemical factors associated with increased body adiposity (BMI > 25 kg/m2 and increased waist circumference: > 80 cm for women and > 94 cm for men). Variables positively and significantly associated with overweight and abdominal obesity in men according to prevalence ratio (PR) values were: age (1.02), high family income (1.05), smoking (1.36), hypertension (systolic blood pressure, 1.41; diastolic blood pressure, 1.85) and hypertriglyceridemia (2.29). In women, the PR of increased body adiposity was associated with: age (1.02), alcohol intake (1.42), hypertriglyceridemia (1.44), diastolic blood pressure (1.65) and hyperglycemia (1.71). CONCLUSIONS: The association of overweight and abdominal obesity with social behavior variables should be corrected with preventive and educational measures. Furthermore, association of overweight and abdominal obesity with clinical and biochemical variables places the urban workers from the Amazon region assisted by the Workers´ Food Program at a possible risk for morbidity and mortality from increased body adiposity.
Acesso aberto (Open Access)
Flavonóides de Cissus verticillata e a atividade hipoglicemiante do chá de suas folhas
(2002) BARBOSA, Wagner Luiz Ramos; SANTOS, Wallace Raimundo Araujo dos; PINTO, Lucianna do Nascimento; TAVARES, Isabel Cecília de Castro
Cissus verticillata, a Vitaceae very used in the traditional medicine in Pará and Minas Gerais State – Brazil, was investigated in order to validate its indication for the hyperglycaemia control. The aqueous extract reduces the normal glycaemia of male white Wistar rats in about 19.5 %. The hypoglycaemic effect of this extract could be related to the flavonoids found in the preparation. Luteolin, Kaempferol and Luteolin-3'-sulphate could be isolated from the aqueous extract after acid hydrolysis. Cissus
Acesso aberto (Open Access)
Primary endemic Cryptococcosis gattii by molecular type VGII in the state of Pará, Brazil
(2008-12) SANTOS, Wallace Raimundo Araujo dos; MEYER, Wieland; COSTA, Solange do Perpétuo Socorro Evangelista; TRILLES, Luciana; NASCIMENTO, José Luiz Martins do; SOUSA, Rita Catarina Medeiros; MORALES, Bernardina Penarrieta; BEZERRA, Cláudia de Carvalho Falci; MACÊDO, Regina Célia Lima de; FERREIRA, Silvana O.; BARBOSA, Gláucia Gonçalves; PEREZ, Mauricio de Andrade; NISHIKAWA, Marília Martins; LAZÉRA, Márcia dos Santos
In order to study the infectious agents causing human disseminated cryptococcosis in the state of Pará, North Brazil, 56 isolates of Cryptococcusspp. (54 isolated from cerebral spinal fluid and two from blood cultures) from 43 cases diagnosed between 2003-2007 were analysed. The species were determined through morphological and physiological tests and genotypes were determined by URA5-RFLP and PCR-fingerprinting (wild-type phage M13). The following species and genotypes were identified: Cryptococcus neoformans VNI (28/56, 50%), Cryptococcus gattii VGII (25/56, 44.64%) and C. gattii VGI (3/56, 5.26%). The genotype VNI occurred in 12 out of 14 HIV-positive adults, whereas the genotype VGII occurred in 11 out of 21 HIV-negative adults (p < 0.02, OR = 6.6 IC95% 0.98-56.0). All patients less than 12 years old were HIV negative and six cases were caused by the VGII genotype, one by the VGI and one by VNI. Therefore, endemic primary mycosis in HIV-negative individuals, including an unexpectedly high number of children, caused by the VGII genotype deserves further study and suggests the need for surveillance on cryptococcal infection in the state of Pará, Eastern Amazon.