Navegando por Assunto "Aedes aegypti"
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Item Acesso aberto (Open Access) Atividade imunomoduladora e antioxidante da saliva do Aedes aegypti em modelo de sepse(Universidade Federal do Pará, 2017-07-04) GOMES, Rafaelli de Souza; MONTEIRO, Marta Chagas; http://lattes.cnpq.br/6710783324317390Sepsis is an organ dysfunction caused by a dysregulated immune response to an infection, the initial therapeutic approach to sepsis are broad spectrum antimicrobials, which is not sufficient for control of infection, requiring association with other therapies focused in the interruption of the inflammatory response chain, provided by the pathogens. In this way, the Aedes Aegypti’s saliva presents immunomodulary features, with a potential pro inflammatory cytokine inhibition, as well as the presence of nitric oxide peptides activators. Therefore, it would be a great interest to search the saliva’s immunomodulator effect in animal model sepses. In this regards, mices were pre treated with Aedes aegypti saliva, and sepsis was induced by the cecal ligation and puncture. After 12 and 24 hours, the samples were collected, and evaluated the survival rate, bacteria level, leukocyte migration, and oxidative parameters (NO, EROs, MDA e TEAC). The saliva improved the animal prognostic, increasing the survival rate and weight. Furthermore, decreased the bacterial levels and increased the influx of monocytes. The saliva, in addition, presented antioxidant effects by reducing production of the reatives species, and increasing the antioxidant capacity, other than decrease the lipid peroxidation. Thus, the saliva was capable to inhibit damages caused by sepsis in animals in vivo, improving its prognostic.Item Acesso aberto (Open Access) A comparison of larval, ovitrap and MosquiTRAP surveillance for Aedes (Stegomyia) aegypti(2013-12) RESENDE, Marcelo Carvalho de; SILVA, Ivoneide Maria da; ELLIS, Brett Richard; EIRAS, Álvaro EduardoIn Brazil, the entomological surveillance of Aedes (Stegomyia) aegypti is performed by government-mandated larval surveys. In this study, the sensitivities of an adult sticky trap and traditional surveillance methodologies were compared. The study was performed over a 12-week period in a residential neighbourhood of the municipality of Pedro Leopoldo, state of Minas Gerais, Brazil. An ovitrap and a MosquiTRAP were placed at opposite ends of each neighbourhood block (60 traps in total) and inspections were performed weekly. The study revealed significant correlations of moderate strength between the larval survey, ovitrap and MosquiTRAP measurements. A positive relationship was observed between temperature, adult capture measurements and egg collections, whereas precipitation and frequency of rainy days exhibited a negative relationship.Item Acesso aberto (Open Access) Estudo das relações entre as variáveis ambientais e a incidência de dengue nos municípios de Santarém, Tucuruí e Bragança ( Pará ), no período de janeiro/2007 a julho de 2011(Universidade Federal do Pará, 2014) BAÍA, Sandra Suely da Veiga; CRUZ, Ana Cecília Ribeiro; http://lattes.cnpq.br/8080838290715777Dengue is a disease with a higher incidence in Brazil, is considered a public health problem and is widely distributed in tropical countries, where environmental conditions favor the proliferation of the Aedes aegypti mosquito that transmits dengue. This study aimed to: determine the demographic profile (gender, age) of dengue cases in the municipalities of Pará: Santarém, Tucuruí and Bragança; investigate the influence of environmental change (deforestation), with the occurrence of dengue in cities studied, and correlate climate change in each area studied, with the process of dengue virus endemicity. This is a study of the ecological, epidemiological type within a retrospective and descriptive study. The study period comprises from January 2007 to July 2011. We used data regarding the incidence of the disease, the Notifiable Diseases Information System ( SINAM ), with the record of 7,871 notifications of dengue, the Department of Public Health of the State of Pará ( SESPA ), as well as environmental and climatological data, Institutes of the environment of the State of Pará in the data analysis, it was evident that the age group most affected by dengue was 21-30 years, which is related to social and economic damage to the country, considering that this band age, are the most economically active people. The study was also obtained, patients suffering from dengue, have on average 29.38 years. The study found that in females, there was a higher incidence of dengue cases. This is expected, as some scholars relate to the fact that women stay at home more, and is commonly occurs in households where disease transmission In regarding the incidence of dengue, Gauteng had the highest number of cases. With regard to this information, it should be emphasized that the municipality has triple the number of inhabitants of the other two municipalities. As for deforestation variable, which was accounted for Santarem, had the highest deforested area in all years of study this fact, which can also be attributed in part to deforestation for soy cultivation. Regarding climatic factors, it was found that the periods of highest rainfall, corresponded to the first months of the year (January to May), and also in this period there was a higher incidence of the disease, possibly due to increased rainfall. As for factors insolation and minimum temperature, it was found that there was no direct relationship between the variables with the increase of dengue cases. With respect to maximum temperature, Gauteng showed a strong correlation between the variables, since the other cities studied showed negative correlation in the study period.Item Acesso aberto (Open Access) A metodologia da problematização: uma sequência didática acerca da temática dengue.(Universidade Federal do Pará, 2023-02-28) RIBEIRO, Elivaldete Baía; SILVA, Ronaldo Adriano Ribeiro da; http://lattes.cnpq.br/2020211060475648; https://orcid.org/0000-0002-4974-4620This research aimed to present studies about dengue, a disease transmitted by the Aedes aegypti mosquito, as well as interdisciplinary activities to foster debate on this topic in all sectors of society and, especially, within school spaces. To instrument the data collection, a didactic sequence was applied, whose objective was to verify the contributions that this methodology can bring to the teaching and learning process, stimulating the formation of knowledge multipliers in the school environment and in other spaces of coexistence. The experiences of the didactic sequence were carried out at the Municipal School Palmira Lins de Carvalho, in Belém - PA, with students of the 5th year of Elementary School and generated the final product of this research. During data analysis, bibliographical, exploratory and qualitative research was used, focusing on the Problematization Methodology, using Maguerez's Arch as a basis, with collection techniques and analysis of participant observation. The data collection instruments were obtained from the field work with the application of the didactic sequence, which was developed in six meetings of two class hours each. The educational product generated was called: ―The Problematization Methodology: a didactic sequence about the dengue theme‖. The development of all the work and the validation stage of the educational product showed that the didactic sequence effectively contributed to the construction of knowledge in Environmental Sciences and enhancing the development of socio-discursive skills, for the interaction and instrumentalization of the students, motivating them to take decision-making and involvement in collective issues, as well as providing more dynamic, interactive and contextualized classes, providing meaningful and relevant learning moments for students and educators.