Navegando por Assunto "Cestrum laevigatum"

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Acesso aberto (Open Access)
Intoxicação experimental por Cestrum laevigatum em bubalinos (Bubalus bubalis)
(Universidade Federal do Pará, 2010-07-01) MARQUES, Débora Maria Marquiori; BARBOSA NETO, José Diomedes; http://lattes.cnpq.br/1516707357889557; RIVERO, Gabriela Riet Correa; http://lattes.cnpq.br/7540534565167837
The aim of this study was to determine the toxicity of Cestrum laevigatum for buffalos and characterize the clinical and pathological intoxication. Were used four Murrah buffaloes divided into two groups. Group 1 (buffalo 1 and 2) received 20g/kg of dried leaves of Cestrum laevigatum fed orally, whereas group 2 (buffalo 3 and 4) received 40g/kg. Buffalo 1 (group 1) showed mild clinical signs, characterized by a reduction of ruminal movements and recovered 60 hours after onset of clinical symptoms. Buffalo 2 (group 1) showed no signs. Buffaloes 3 and 4 (Group 2) showed the first signs 26h05min and 37h22min after the end of the administration, respectively. Clinical signs of intoxication were lethargy, anorexia, decrease or absence of ruminal movements, drooling, difficulty breathing, staggering gait, dysmetria, excitement, aggression, constipation, with stools containing mucus and blood, groans, dry nose, drowsiness, paddling movements and death in 44h11min (buffalo 3) and 60h39min (buffalo 4) after administration of the plant. At necropsy, Buffalo 3 revealed capsular and cut surface of liver brownish orange, mild edema of the gallbladder wall, left ventricular endocardium with extensive haematomas and endocardium of the right ventricle with a few petechiae, abomasum mucosa slightly reddish; contents abomasum slightly dry, large intestine with little content slightly dry and surrounded by mucus. In Buffalo 4 capsular and cut surface of liver colored orange, with a clear aspect of nutmeg , mild edema of gallbladder wall, mild splenomegaly, slightly reddish mucosa of the abomasum, small intestine content catarrhal and mucous, and slightly congested meninges. Histologically, the liver of both animals demonstrated marked coagulation and necrosis of hepatocytes in central and intermediate lobular zones and vacuolization of hepatocytes close to the areas of necrosis.
Acesso aberto (Open Access)
Intoxicação por Cestrum laevigatum (Solanaceae) em bubalinos
(2010-12) BARBOSA NETO, José Diomedes; OLIVEIRA, Carlos Magno Chaves; PINHEIRO, Cleyton Prado; LOPES, Cinthia Távora de Albuquerque; MARQUES, Débora Maria Marquiori; BRITO, Marilene de Farias; YAMASAKI, Elise Miyuki; TOKARNIA, Carlos Maria Antônio Hubinger
Based on the history and clinical and pathological data, as well as on inspection of the pastures, a mortality of buffaloes in the county of Itaguaí/RJ, Brazil, was diagnosed as poisoning by Cestrum laevigatum Schlecht., a plant of the Solanaceae family. The poisoning was reproduced in two buffaloes. Dried leaves of the shrub were administered by hand, in single doses corresponding to 20g/kg and 40g/kg of the fresh leaves, to four buffaloes of the Murrah breed. The dose corresponding to 40g/kg of the fresh leaves caused signs of poisoning, as apathy, anorexia, absence of rumen movements, dysmetria, excitement and aggressiveness, followed by death of the two buffaloes within 65 hours after administration. From the two buffaloes that received the corresponding dose of 20g/kg of the fresh plant, one presented clinical signs characterized mainly by decrease of the rumen movements, but recovered 97h22min after the administration; the other buffalo did not show symptoms of poisoning. Laboratory analyses for biochemical evaluation accused hepatic alterations. In one buffalo that died, the main macroscopic finding was an orange liver with a clear nutmeg appearance; in the second buffalo, the orange liver had no nutmeg appearance. Other alterations found in these two buffaloes were slight edema of the gall bladder wall, a slightly reddish mucous membrane of the abomasum, extensive echymoses in the endocard of the left ventricle and few petechiae in the endocard of the right ventricle; the abomasum content was slightly dry, and the large intestine had little and slightly dry contents wrapped by mucus. Histopatological examination revealed severe coagulative necrosis of the liver parenchyma in the centrolobular and intermediate lobular areas, with a halo of vacuolated hepatocytes at the periphery of the necrotic areas.