Navegando por Assunto "Consumo de bebidas alcoólicas"
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Item Acesso aberto (Open Access) Atitudes e comportamentos de adolescentes em relação à ingestão de bebidas alcoólicas(Universidade Federal do Pará, 2011-10) SILVA, Sílvio Éder Dias daItem Acesso aberto (Open Access) Minociclina atenua os prejuízos motores em ratos submetidos à isquemia focal no córtex motor e expostos cronicamente ao etanol da adolescência à fase adulta(Universidade Federal do Pará, 2012-08-30) OLIVEIRA, Gedeão Batista de; MAIA, Cristiane do Socorro Ferraz; http://lattes.cnpq.br/4835820645258101According to World Health Organization, alcohol consumption in the world has become a public health problem. In this context, Brazil is at 63th position in the world in per capita alcohol consumption for people aged 15 or older. In addition to its socio-economic effects, ethanol is an important risk factor in the occurrence of cerebral ischemia. Exacerbated consumption of this drug contributes to the poor prognosis, as well as possible treatment for health problems related to stroke. The objective of this study was to evaluate neuromotor changes after blocking micróglial activation with minocycline in rats subjected to focal ischemia in the motor cortex, when treated chronically with ethanol from adolescence to adulthood. Rats were given for 55 days by gavage ethanol (6.5 g/kg/dia, 22.5 w/v). At the end of 55 days the animals were microinjected with the vasoconstrictor peptide endothelin-1 (40 pmol) for induction of focal ischemic lesion. The ischemic animals were treated with minocycline receiving two daily doses of 50 mg/kg in the first two days, and five daily applications of single 25mg/kg, intraperitoneally, by the seventh day post-ischemic induction. Behavioral tests consisted of open field, inclined plane and rota-rod. The results showed that the animals were exposed to ethanol showed motor deficits in all behavioral tests. However, treatment with minocycline was able to reverse them, enabling better performance on all tests. The results suggest that minocycline was able to reverse damage caused by motors stroke, even in the presence of ethanol. The exact mechanism involved in this process need to be investigated in future research.Item Acesso aberto (Open Access) Validação de indicadores do consumo de alimentos e bebidas obtidos por inquérito telefônico em Belém, Pará, Brasil(2010-12) NEVES, Alice Cristina Medeiros das; GONZAGA, Lidyane Andrea Amaral; MARTENS, Irland Barroncas Gonzaga; MOURA, Erly Catarina deThe aim of this study was to evaluate the relative validity of indicators of food and beverage intake obtained from the telephone interview surveillance system (VIGITEL). A random sample (n = 100) was evaluated from the total sample of approximately two thousand adults studied by the system in 2009 in Belém, Pará State, Brazil. The indicators were protective factors (adequate consumption of fruit, vegetables, and leafy vegetables) and risk factors (consumption of saturated fat, soft drinks, and alcoholic beverages) for chronic non-communicable diseases. The telephone interview results were compared with those of three 24-hour recalls (reference standard). The reference standard showed underestimation in the indicators' frequency, except for soft drinks and alcoholic beverages. The mean consumption frequencies were generally higher in the exposed group interviewed by the VIGITEL system. We cannot conclude that the VIGITEL system is not a good indicator of consumption, since the reference standard also shows limitations. Nevertheless, its use as a surveillance tool in Brazil is justifiable.