Navegando por Assunto "Contraste de luminância espacial"

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Acesso aberto (Open Access)
Diminuição da sensibilidade ao contraste espacial de luminância em sujeitos com história de uso de terapia medicamentosa anti-tuberculose
(Universidade Federal do Pará, 2012) GOMES, Janildes Maria Silva; SOUZA, Givago da Silva; http://lattes.cnpq.br/5705421011644718
The drugs isoniazid and ethambutol, usually administed for tubercolosis treatment, are well known to cause damage in the visual system of the patients that use them. As vision is an important sense for the quality of life and the luminance contrast is considered a good biomarker for visual evaluation, the present study aimed to compare the contrast sensitivity estimated from subjects that used anti-tuberculosis drug therapy and age-matched healthy subjects. The study was performed in Imperatriz city, Balsas city, Davinópolis city and Governador Edson Lobão city, in Maranhão state, Brazil from 2009 to 2012. The current study had a transversal, analytic, and case control profile. Three group of subjects participated from the present study: Control group (n=40), group of subjects treated with isoniazid (n = 19), and group of subjects that used isoniazid associated with ethambutol (n=18). It was used a CRT monitor, 21”, 6 x 5 degrees of visual angle to investigate the contrast sensitivity function. The comparison of the contrast sensitivities at different spatial frequencies among the three studied groups showed statistical differences (Two-way ANOVA, Tukey test, p < 0,05). Control group had higher contrast sensitivity at 10 and 15 cpd than the group that used only isoniazid as drug therapy for tuberculosis treatment and control group had higher contrast sensitivity at 4, 6, 10, 15 and 20 cpd than the group the received isoniazid and ethambutol together. There were no differences between the groups that received anti-tuberculosis therapy.
Acesso aberto (Open Access)
Perda de sensibilidade ao contraste espacial de luminância em sujeitos com história clínica de hipovitaminose B1
(Universidade Federal do Pará, 2012) LOBATO, Jaisane Santos Melo; SOUZA, Givago da Silva; http://lattes.cnpq.br/5705421011644718
Vitamin B1 acts directly in the energetic metabolism and its deficiency causes several deficits to the nervous system, including those that occurs in vision that is an important and fundamental sense in the quality of life of the human beings. Studies have been shown that the contrast sensitivity estimative is a good biomarker for evaluation of the visual system and the own nervous system. The present study purposed to compare the contrast sensitivity of subjects with history of hypovitaminosis B1 with healthy subjects living in the cities of Imperatriz and João Lisboa in the Maranhão state from 2006 to 2009. This is a transversal, analytic, and case control study. It was investigated 18 patients with history of hypovitaminosis B1 (13 males, 5 females) with mean age 33.77 ± 9.33 years-old, whose had 35 eyes. The control group was composed by 40 subjects (80 eyes) from both sexes, and mean age 33.25 ± 9.3 years-old. Both groups had similar way of life. For psychophysical evaluation, it was used cathodic ray tubes, 21”, 6 x 5 degrees of visual angle. It was performed a nutritional evaluation of all investigated subjects, further visual acuity and contrast sensitivity evaluation. There were statistical differences between the contrast sensitivity of the control group and the group of the subjects with history of hypovitaminosis B1 at 4, 10, 15 e 20 cpd (two-way ANOVA, α = 0,05, Tukey post-hoc test). Most of the subjects with changes in healthy nutritional condition had changes in the visual evaluation. Clinical complains also had important relationship with visual losses.