Navegando por Assunto "Euphorbiaceae"

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Acesso aberto (Open Access)
Molecular characterization of 'sweet' cassavas (Manihot esculenta) from a germplasm bank in Brazilian Eastern Amazonia
(Sociedade Brasileira de Melhoramento de Plantas, 2016-03) CUNHA, Elisa Ferreira Moura; SILVA, Carlos Rogério de Sousa; ALBUQUERQUE, Paulo Sérgio Bevilaqua de; RAMALHO, Girena Fernandes; PONTES, Lígia Cristine Gonçalves; FARIAS NETO, João Tomé de
Genetic variability of a set of 81 accessions of 'sweet' cassavas (Manihot esculenta) collected mostly in the North region of Brazil was investigated with nine microsatellite loci. All loci were polymorphic, with mean of 6.33 alleles per locus. Analyses indicated that 35 multiloci profiles were represented by a single accession, and 46 showed non-unique profiles, represented by eleven genotypes. Forty-six different multiloci profiles were detected. Most of the putative duplicated accessions were collected in different locations. After the removal of putative duplicated genotypes, genetic parameters were estimated and expected heterozygosity was high (HE=0.73), indicating genetic variability. Structure analysis of this set of 'sweet' cassavas divided the 46 genotypes into two clusters (K=2), and a few genotypes had mixed ancestry. Results indicated the habit of exchange of materials among farmers of the North region of Brazil, and the genetic variability to be exploited in genetic breeding efforts.
Acesso aberto (Open Access)
Poderia um óleo atuar como analgésico opioide? oléo de Plukenetia polyadenia: elucidação do mecanismo de ação
(Universidade Federal do Pará, 2016-09-05) MOTA, Amanda Sodré; MAIA, Cristiane do Socorro Ferraz; http://lattes.cnpq.br/4835820645258101; BASTOS, Gilmara de Nazareth Tavares; http://lattes.cnpq.br/2487879058181806
The seed oil of Plukenetia polyadenia (Pp-oil) is used by the Amazon people against arthritis and rheumatism, spreading it in the arms and legs. The fatty acid composition, antinociceptive effect and toxicity of Pp-oil were investigated. Materials and methods: The Pp-oil was obtained by pressing and its antinociceptive activity was analyzed in models of nociception (acetic acid-induced abdominal writhing, hot plate and formalin tests) in mice and also mechanism of action was determined using acetic acid- indiced abdominal writing, open field, pole test and rotarod. Results: Pp-oil demonstrated a significant dose dependent antinociceptive effect (p< 0.05) in the chemical stimulation and at the second phase of formalin. However, the result from the hot plate test, open field, pole test and rotarod were not significant (p> 0.05), suggesting that Pp-oil has an analgesic activity, which is putative of peripheral origin. In the writhing test, the oil dosed at 25, 50 and 100 mg/kg reduced the abdominal writhes in a significant manner. In the hot plate test, the oil dosed at 200 mg/kg did not induced alterations in the latency time when compared to the control. At the dose of 100 mg/kg it did not show any difference in motor system proving that Pp-oil does not have any influence at central nervous system. In the formalin test, the oil dosed at 50 and 100 mg/kg reduced in a significant manner the second phase of the algic stimulus. Pp-oil at 100mg/kg did not show any alterations in motor system when analyzed with open field, pole test and rotarod (p>0,05), which corroborates with previous results that affirm Pp-oil has no participation in central nervous system. In addition, its antinociception was reversed by naloxone in evaluation of the mechanism of action. Conclusion: Pp-oil proved to have analgesic properties. Moreover, the results concerning mechanism suggest that opiod receptors are involved in the antinociceptive action of the Pp-oil using a peripheral pathway.