Navegando por Assunto "Medicina fitoterápica"

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Acesso aberto (Open Access)
Evaluation of antinociceptive and antiinflammatory effects of Croton pullei var. glabrior Lanj. (Euphorbiaceae)
(2008-09) ROCHA, Fabio Fagundes da; NEVES, Evandro Manoel Neto; COSTA, Elson Alves; MATOS, Lécia Garcia de; MÜLLER, Adolfo Henrique; GUILHON, Giselle Maria Skelding Pinheiro; CORTES, Wellington da Silva; VANDERLINDE, Frederico Argollo
Croton pullei var. glabrior Lanj. (Euphorbiaceae) is a liana, vastly distributed in the Amazonian Forest. In the folk medicine, several plants of the Croton genus have been used with therapeutic purposes in pathologies that involve painful and inflammatory diseases which justify this work. The aim of this study was to investigate the antinociceptive and antiinflammatory activities of the C. pullei leaves methanol extract (MECP). MECP reduced in a dose-dependent manner the number of acetic acid-induced abdominal writhing (1.2%) in mice, suggesting an antinociceptive activity of the plant. On the other hand, MECP did not significantly modify the reactivity to the thermal stimulation in the hot-plate test and the reactivity to the chemical stimulation in the formalin test first phase, indicating a non-opioid mechanism. MECP reduced the formalin-induced nociception in the second phase, inhibited the croton oil-induced ear edema and reduced the leukocytes migration in the test of the carrageenan-induced peritonitis, indicating an antiinflammatory activity. Although the mechanisms that underlie these plant effects are not completely elucidated, these results appear to support the potential medicinal use of Croton pullei var. glabrior Lanj. against painful and inflammatory diseases.
Acesso aberto (Open Access)
Uso medicinal da pimenta malagueta (Capsicum frutescens L.) em uma comunidade de várzea à margem do rio Amazonas, Santarém, Pará, Brasil
(Universidade Federal do Pará, 2011-12) ROMAN, André Luís Cote; MING, Lin Chau; ARAUJO, Izabel Carvalho de; SABLAYROLLES, Maria das Graças Pires
An ethnobotanical study was carried out for this study aimed at understanding the medicinal importance of malagueta / chili pepper (C. frutescens L.) in the daily life of the people of Cabeça D'Onça, an area in the Amazon River floodplain. The community of approximately 330 residents is situated in the municipality of Santarém, Pará State. In total, 116 people from 70 households were interviewed for this work. Information regarding the medicinal uses of these peppers was collected in semi-structured interviews and compiled in detail. In the second phase of the study, structured interviews were carried out in 40 households with 80 people (40 couples) to determine the most commonly-known uses of the peppers in the study area. Over 50% of those interviewed cited the use of the malagueta in curing certain illnesses reputed to be caused by contact with water from the Amazon River, including 'pano-branco', and 'impinge' (both diseases of the skin treated with the leaves) and rheumatism (treated with the fruit). A comparison of the data obtained in this study with published literature reveals strong indigenous influence in their medicinal use.