Navegando por Assunto "Neoplasia intra-epitelial cervical"

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Estudo da frequência das neoplasias intra-epiteliais cervicais em mulheres portadoras do vírus da imunodeficiência humana
(Universidade Federal do Pará, 2003) AZEVEDO, Valéria Nascimento da Gama; FRAIHA NETO, Habib; http://lattes.cnpq.br/9202245658963683; LIMA, Fábio André Souto; http://lattes.cnpq.br/1304485376972715
Cervical cancer and its prescursor lesions are the most important gynecologic manifestations of human immunodeficiency virus infection. Thirty six women infected with human immunodeficiency vírus (HIV) and fifty four uninfected were studied to evaluate the frequency by cervical squamous intraepithelial lesions (SILs), the precursors to invasive cervical cancer. All pacients were interviewed and had a gynecologic examination including Papanicolaou (Pap) test and colposcopy. Biopsies were done on colpocopic abnormalities. The CD4 cell levels were assessed in HIV infected women and we asked about use of antiretrovíral therapy on incidence of SILs, and almost all them used the drugs. The results showed that the frequency of SILs was similar in the two groups. The most of infected women had CD4 levels over than 200 cells/mm3. They were considered immunocompetent. And thirty three women trom thirty six used antiretroviral therapy. In our study the women infected with human immunodeficiency virus, using antiretroviral therapy, with immunocompetent status, had the same frequency of SILs observed on uninfected women.
Acesso aberto (Open Access)
Papilomavírus humano associado a lesões de cérvice uterina
(1999-06) CAVALCANTE, Vânia Lúcia Noronha; MELLO, Wyller Alencar de; VILLA, Luísa Lina; BRITO, Arival Cardoso de; MACEDO, Roberto Cavalleiro de; BISI, Fátima; SASSAMOTO, Kyio; MONTEIRO, Talita Antonia Furtado; LINHARES, Alexandre da Costa
It was studied the prevalence of human papillomavirus (HPV) among 228 women with lesions of uterine cervix attending the Ofir Loiola Institute, in Belem, Para, from March 1992 to May 1996. Histopathological examination was performed with all cervical biopsy samples obtained from these patients. In addition, specimens were analysed by both polimerase chain reaction and dot-blot hybridization to detect HPV DNA. The patients were assigned to three groups, according to the diagnosis made by histopathology, as follows: A, including 155 women suffering from invasive epidermoid carcinoma or adenocarcinoma; B, 54 patients having either cervical intraepithelial neoplasia grade II or III; and C, involving 19 women with chronic cervicitis. The prevalence rates of HPV in groups A, B and C were 70.3%, 63% and 36.8% respectively. HPV 16 accounted for 60.4% and 54.5% of types identified in groups A and B, respectively. Altogether HPV types 16, 18 and 33 were detected in 71.4% of positive patients belonging to group C.