Navegando por Assunto "Paracoccidioidomicose"

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Acesso aberto (Open Access)
Effect of serum sample inactivation on the performance of latex agglutination test for paracoccidioidomycosis serodiagnosis
(2012-06) GOMES, Fabíola Silveira; SILVA, Silvia Helena Marques da
Paracoccidioidomycosis is diagnosed from the direct observation of the causative agent, but serology can facilitate and decrease the time required for diagnosis. The objective of this study was to determine the influence of serum sample inactivation on the performance of the latex agglutination test (LAT) for detecting antibodies against Paracoccidioides brasiliensis. The sensitivity of LAT from inactivated or non-inactivated samples was 73% and 83%, respectively and the LAT selectivity was 79% and 90%, respectively. The LAT evaluated here was no more specific than the double-immunodiffusion assay. We suggest the investigation of other methods for improving the LAT, such as the use of deglycosylated antigen.
Acesso aberto (Open Access)
Inquérito com paracoccidiodina em cinco cidades do Estado do Acre
(Universidade Federal do Pará, 2011-09-30) FIGUEIREDO, Mediã Barbosa; ISHAK, Ricardo; http://lattes.cnpq.br/5621101706909450
Paracoccidioidomycosis constitutes an important public health problem in Latin America. In Brazil, this disease is less frequent in North and Northeast regions, predominating the endemic areas in the Southeast. Despite the physiographic conditions of the North region favoring the development of Paracoccidioides brasiliensis, even so, the case reports are scarce. Perhaps this is due to the little consideration of deep mycoses about the differential diagnosis of chronic medical conditions, justified by the fact that the region is not considered endemic. With the objective of describing the prevalence of paracoccidioidomycosis in five cities of Acre, a cross-sectional population-based study was conducted, through a survey with the paracoccidioidin intradermal. The reading of the intradermal test was performed within 24 and 48 hours, being considered reactors the people with hardened areas of 5mm or more in diameter. Four hundred thirty-nine (439) people were studied and paracoccidiodomycosis-infection in the 48-hour reading was 41.2%. The findings of this study indicate that P. brasiliensis infection causes a considerable number of people in the study area to get infected, and therefore future clinical-epidemiological and mycological studies should better clarify the natural history of mycosis in this region.
Acesso aberto (Open Access)
Paracoccidioidomicose em crianças em Belém do Pará
(1999-02) FONSECA, Eliane Regine de Souza da; PARDAL, Pedro Pereira de Oliveira; SEVERO, Luiz Carlos
During the period from January/85 to July/96, 102 cases of paracoccidioidomycosis were observed in a hospital in Belém, PA. Thirteen of these cases were children between 3 and 13 years of age, with a predominance of females (8:5). All patients presented the disseminated subacute form of the mycosis. The high prevalence of the mycosis in children in endemic areas of the Amazon region is discussed.