Navegando por Assunto "Petiveria alliacea"

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Desconhecido
Avaliação antifungica, farmacognóstica e toxicológica sazonal de Petiveria alliacea L. (Phytolaccaceae)
(Universidade Federal do Pará, 2012-12-20) OLIVEIRA, Fábio Rodrigues de; GONÇALVES, Ana Cristina Baetas; http://lattes.cnpq.br/6886126078022769; ANDRADE, Marcieni Ataíde de; http://lattes.cnpq.br/8514584872100128
The study of medicinal plants raised great scientific interest, mainly due to them being considered as potential sources of bioactive molecules with differentiated structure and new mechanism of action. The importance of research focused on the discovery and production of new herbal medicines should be the great contribution they have presented before diverse pathologies. The species Petiveria alliacea is a medicinal plant widely used by the population of the Amazon region and stands out for presenting various claims and still use some classes of metabolites with proven therapeutic actions. This study aimed to evaluate seasonal pharmacognostical parameters, antifungal potential of the extracts produced at different sampling times on Aspergillus species and toxicity of these in vitro and in vivo. In the evaluation of seasonal Pharmacognostical, P. alliacea, using Brazilian Pharmacopeia methods the results demonstrated reproducible parameters for quality control of the plant drug, there was no difference in the presence of the chemical constituents of hydroalcoholic and dust, revealing the presence of saponins, alkaloids and sugars across the plant and root extracts and only sesquiterpenolactones depsides. The results of microdilution method performed with extracts from the roots of two periods, showed weak antifungal activity in vitro, but did not observe any effect of extracts of the aerial parts. The cytotoxicity was evaluated by MTT colorimetric method, showed that the hydroalcoholic extract of the root of the two periods did not reduce cell viability in any of the concentrations tested, and was any signs of acute toxicity of the extract at a dose of 5000 mg/kg in mice. These data are considered relevant and the current study showed that P. alliacea is a promising medicinal species, but further investigations are required for its various allegations are confirmed and usage for the plant to be used in developing a new phytotherapeutic agent.
Desconhecido
Avaliação dos efeitos no sistema nervoso central e estresse oxidativo do extrato hidroalcoólico de Petiveria alliacea L. (Phytolacaceae)
(Universidade Federal do Pará, 2011) ANDRADE, Thaís Montenegro de; MONTEIRO, Marta Chagas; http://lattes.cnpq.br/6710783324317390; MAIA, Cristiane do Socorro Ferraz; http://lattes.cnpq.br/4835820645258101
Acesso aberto (Open Access)
Petiveria alliacea L.: etnobotânica, fitoquímica efeitos neurofarmacológicos e cognitivos
(Universidade Federal do Pará, 2016-10-16) LUZ, Diandra Araújo da; MAIA, Cristiane do Socorro Ferraz; http://lattes.cnpq.br/4835820645258101
Petiveria alliacea L. is a shrubby plant, native from tropic regions, used to treat poor memory and improve learning. In the present study, it was evaluated the effects of hydroalcoholic extract of the leaves of P. alliacea (PaLHE, 900 mg/kg) on learning and memory of adult rats, subjected to behavioral tests inhibitory avoidance and Morris Water Maze. In addition, it was performed a thin layer chromatography (TLC) to detect sulphur compound, to correlate them with the investigated responses. Dichloromethane fractions, obtained from aqueous extracts of Alllium sativum and Allium Cepa served as detection patterns. P. alliacea is also present controversial activities on central nervous system (CNS). For this reason, it was realized a bibliographic review of ethnobotanical, phytochemical and neuropharmacological activities of this plant in indexed databases, books, dissertations, thesis and similar scientific sources. According to the results, EHFPa improved short and long term memory, spatial memory and learning. In TLC, the EHFPa produced retention points similar to the standard samples, indicating that there are sulfur compounds in the extract, being possible that they contribute to observed responses. About the review, P. alliacea is popularly used to treat epilepsy, anxiety, poor memory, as a sedative, etc. Such properties have been demonstrated experimentally, varying depending on the dose, preparation, and part of plant used. Phytochemical studies detected several metabolites in P. alliacea, among which sulfur compounds, flavonoids and derivatives classes the most isolated compounds.