Navegando por Assunto "muscle strength"

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Determinantes de sarcopenia e fragilidade em pessoas com Parkinson no contexto amazônico
(Universidade Federal do Pará, 2025-03-26) SANTOS, Ana Carla de Matos; MONTEIRO, Elren Passos; http://lattes.cnpq.br/0920248966438368; https://orcid.org/0000-0001-7757-6620
Introduction: Aging is a natural process characterized by the progressive loss of tissue and organ function, increasing the predisposition to various diseases, including Parkinson's Disease (PD). Among the conditions associated with PD, sarcopenia and frailty stand out as relevant geriatric syndromes. Sarcopenia is defined by the progressive reduction of muscle mass, strength, and function, while frailty is characterized by greater vulnerability to stressors, impacting physiological reserve and functional capacity. Despite distinct concepts, both share pathophysiological mechanisms affecting muscle power, such as chronic inflammation, oxidative stress, and neuromuscular degeneration. The absence of accessible and standardized instruments for screening these geriatric syndromes in clinical settings represents a challenge, especially considering the applicability of these methods in different sociodemographic contexts, such as in the Amazon region. Objective: This study aimed to analyze the profile of sarcopenia and frailty, as well as possible associations with clinical parameters of PD and sociodemographic aspects in people with Parkinson's disease (PwP) living in the community of a state in the Amazon region. Methods: This is an observational and analytical study, including PwP over 40 years of age, of both sexes. Initially, an anamnesis was conducted to collect sociodemographic data, followed by using instruments such as SARC-Calf and Short Physical Performance Battery (SPPB) for sarcopenia screening, and Fried's Phenotype for frailty screening. Vertical power was analyzed using the My Jump 2 app, considering parameters such as jump height, flight time, take-off velocity, force, and power. For statistical analysis, Spearman's correlation coefficient was used to identify possible associations between sarcopenia and frailty with clinical and sociodemographic variables. Subsequently, logistic regression was conducted to assess whether body mass predicted sarcopenia. Regarding frailty, none of the predictors were significant. All analyses were performed using SPSS software (IBM, Greenville, SC), version 25.0. Results: A total of 24 people with Parkinson's disease (PwP) were evaluated, 83.3% of whom were male, with a mean age of 66.35 years, living with a spouse and children (37.5%). They were stratified into sarcopenic (29.2%) and non- sarcopenic (70.8%) groups. An association was observed between sarcopenia and body mass (OR = 1.438; CI = 1.045 – 1.980). Regarding frailty, the prevalence was lower than reported in the literature, possibly due to the small sample size. Conclusion: This study concluded that body mass was a risk predictor for sarcopenia in PwP, and that the sample profile was predominantly male, with a higher occurrence of falls in stage 2 of PD and a high prevalence of pre-frailty. Despite the absence of other significant predictors for sarcopenia and frailty, the findings highlight the need for clinical standardization and universal diagnostic criteria, considering regional sociodemographic aspects.
Acesso aberto (Open Access)
Efeito agudo do HIIT e do alongamento no controle inibitório, desempenho matemático e na variabilidade da frequência cardíaca: Um ensaio randomizado e cruzado
(Universidade Federal do Pará, 2021-07-01) MODA, Tomé Edson dos Reis; COSWIG, Victor Silveira; http://lattes.cnpq.br/0097939661129545; https://orcid.org/0000-0001-5461-7119
Resistance Training (RT) is a modality that has high applicability and efficiency in physical, clinical and functional contexts. The scientific advance in this modality, a series of recommendations for the manipulation of variables and dosage of RT emerged for different purposes and population. However, it is not clear how these RT prescription guidelines affect responsiveness, characterized like an individual's particular capacity for respond to/benefit from an intervention, for a given measure. Therefore, the aim of the study was to carry out a systematic review to investigate the effect of RT on the responsiveness of healthy adults, in variables of strength, power, functionality and muscle hypertrophy, based on the prevalence rate. Only randomized clinical trials, in English, indexed in the PubMed/MEDLINE, SCOPUS, EMBASE and SPORTDiscus databases, published until June 2021, were considered. The study was registered in the International Prospective Register of Systematic Reviews (PROSPERO), identified by the code CRD42021265378. After the study selection process, the risk of bias was analyzed using the ROB2 tool from Chrocrane. After the search strategy, 3033 studies were found and, through the screening process, 13 studies were selected for systematic analysis. As for the effectiveness of the RT, the prevalence range for non-responders individuals to muscle strength was 0% to 44%, for hypertrophy 0% and 84% and functionality 0 to 42%, while, for muscle power, only one study investigated the responsiveness rate and reported 37%. Therefore, it seems that alterations to muscle hypertrophy may be less sensitive to RT, compared to other variables. Larger RT volume tends to be more effective overall, however intensity may be a key factor in some cases. However, the principle of specificity can be the most important aspect to effectivity of TR in these variables of interest. Moreover, it is important to consider methodological and statistical aspects when analyzing outcomes in responsiveness.