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dc.creatorBRITO, Marcus Vinicius Henriques-
dc.creatorYASOJIMA, Edson Yuzur-
dc.creatorPÉRCARIO, Sandro-
dc.creatorRIBEIRO JUNIOR, Rubens Fernando Gonçalves-
dc.creatorCAVALCANTE, Lainy Carollyne da Costa-
dc.creatorMONTEIRO, Andrew Moraes-
dc.creatorCOUTEIRO, Rodrigo Paracampo-
dc.creatorRODRIGUES, Ivone Aline da Silva-
dc.creatorSANTOS, Hellen Aparecida Geyer dos-
dc.date.accessioned2019-03-28T22:20:53Z-
dc.date.available2019-03-28T22:20:53Z-
dc.date.issued2017-03-
dc.identifier.citationBRITO, Marcus Vinicius Henriques et al. Effects of hypertonic saline solution associated to remote ischemic perconditioning in kidney ischemia/reperfusion injury in rats. Acta Cirúrgica Brasileira, São Paulo, v. 32, n. 3, p. 211-218, Mar. 2017. DOI: http://dx.doi.org/10.1590/s0102-865020170030000005. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10808. Acesso em:.pt_BR
dc.identifier.issn1678-2674pt_BR
dc.identifier.urihttp://repositorio.ufpa.br/jspui/handle/2011/10808-
dc.description.abstractTo evaluate the effects of hypertonic saline solution associated to remote ischemic perconditioning in renal ischemia/reperfusion injury in rats. Methods: Twenty five male rats (Wistar) underwent right nephrectomy and were distributed into five groups: Sham group (S); Ischemia/Reperfusion group (I/R) with 30 minutes of renal ischemia; Remote ischemic perconditioning group (Per) with three cycles of 10 minutes of I/R performed during kidney ischemia; Hypertonic saline solution group (HSS) treated with hypertonic saline solution (4ml/kg); remote ischemic perconditioning + Hypertonic saline solution group (Per+HSS) with both treatments. After reperfusion, blood samples were collected for BUN and creatinine serum levels analyzes. TBARS were evaluated in plasma and renal tissue to assess oxidative stress. Kidney histopathological examination were performed. Results: Per+HSS group showed a lower degree of renal dysfunction in relation to I/R group, whereas the technique of remote ischemic perconditioning isolated or associated with saline solution significantly reduced oxidative stress and histological damage. Conclusion:Remote ischemic perconditioning associated or not to saline solution promoted reduction of acute renal injury induced by ischemia/reperfusion.en
dc.description.provenanceSubmitted by Amanda Garcia Gomes (amandagarcia.biblio2015@gmail.com) on 2019-03-28T11:43:41Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Articles_EffectsHypertonicSaline.pdf: 1277163 bytes, checksum: 65f6753504cb2f3546d0ddd9e58bb06f (MD5)en
dc.description.provenanceApproved for entry into archive by João Paulo Pastana Neves (joaopastana@ufpa.br) on 2019-03-28T22:20:53Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Articles_EffectsHypertonicSaline.pdf: 1277163 bytes, checksum: 65f6753504cb2f3546d0ddd9e58bb06f (MD5)en
dc.description.provenanceMade available in DSpace on 2019-03-28T22:20:53Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Articles_EffectsHypertonicSaline.pdf: 1277163 bytes, checksum: 65f6753504cb2f3546d0ddd9e58bb06f (MD5) Previous issue date: 2017-03en
dc.languageengpt_BR
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgiapt_BR
dc.relation.ispartofActa Cirúrgica Brasileirapt_BR
dc.rightsAcesso Abertopt_BR
dc.source.urihttp://ref.scielo.org/h7w9mcpt_BR
dc.subjectIschemiaen
dc.subjectReperfusionen
dc.subjectSaline solutionen
dc.subjectHypertonicen
dc.subjectKidneyen
dc.subjectRatsen
dc.titleEffects of hypertonic saline solution associated to remote ischemic perconditioning in kidney ischemia/reperfusion injury in ratsen
dc.typeArtigo de Periódicopt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.initialsSOBRADPECpt_BR
dc.creator.Latteshttp://lattes.cnpq.br/1180984403274256pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/6901845081643218pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/3018367879063988pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/1167494380865334pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/0167070128206206pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/7654781931568404pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/4061334276759843pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/0087163454656687pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/5888407971437272pt_BR
dc.citation.volume32-
dc.citation.issue3-
dc.citation.spage211-
dcterms.citation.epage218-
dc.identifier.doihttp://dx.doi.org/10.1590/s0102-865020170030000005pt_BR
dc.description.affiliationPERCÁRIO, S. Universidade Federal do Parápt_BR
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