Please use this identifier to cite or link to this item: https://repositorio.ufpa.br/jspui/handle/2011/3377
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dc.creatorREBELO, Monaliza Maia-
dc.creatorSILVA, Joyce Kelly do Rosário da-
dc.creatorANDRADE, Eloisa Helena de Aguiar-
dc.creatorMAIA, José Guilherme Soares-
dc.date.accessioned2013-01-24T13:40:07Z-
dc.date.available2013-01-24T13:40:07Z-
dc.date.issued2009-03-
dc.identifier.citationREBELO, Monaliza M. et al. Antioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benth. Revista Brasileira de Farmacognosia, João Pessoa, v. 19, n. 1b, p. 230-235, jan./mar. 2009. Disponível em: <http://www.scielo.br/pdf/rbfar/v19n1b/a09v191b.pdf>. Acesso em: 22 jan. 2013. <http://dx.doi.org/10.1590/S0102-695X2009000200009>.pt_BR
dc.identifier.issn0102-695X-
dc.identifier.urihttp://repositorio.ufpa.br/jspui/handle/2011/3377-
dc.description.abstractThe essential oils of fresh and dried leaves and fine stems of Hyptis crenata furnished the following yields: 1.4% and 0.9%. The main volatile constituents were α-pinene (22.0%; 19.5%), 1,8-cineole (17.6%; 23.2%), β-pinene (17.0%; 13.8%), camphor (4.7%; 11.6%), limonene (5.4%; 4.4%) and γ-terpinene (3.5%; 2.4%), totalizing more than 70% in the oils. The DPPH radical scavenging activity (EC50, 16.7 + 0.4 µg/mL) of the methanol extract was comparable to BHT (19.8 ± 0.5 µg/mL) showing a significant antioxidant activity. The oils showed low activities. The amount of total phenolics (TP, 373.0 + 15.9 mg GAE/g) and trolox equivalent (TEAC, 226.8 + 0.5 mg TE/g) confirmed the antioxidant activity of the methanol extract that can be attributed to the presence of polar phenolic compounds. In the brine shrimp bioassay the lethal concentrations (LC50) for the oil and methanol extract were 6.7 + 0.2 µg/mL and 13.0 + 3.7 µg/mL, respectively, providing important evidence of their biological activities.pt_BR
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dc.description.provenanceMade available in DSpace on 2013-01-24T13:40:07Z (GMT). No. of bitstreams: 2 license_rdf: 23599 bytes, checksum: 9e2b7f6edbd693264102b96ece20428a (MD5) Artigo_AntioxidantCapacityBiological.pdf: 329185 bytes, checksum: 4f73f7d371137cf17d8c0dae2c78d45f (MD5) Previous issue date: 2009-03en
dc.language.isoengpt_BR
dc.rightsAcesso Aberto-
dc.subjectAtividade antioxidantept_BR
dc.subjectÓleo aromáticopt_BR
dc.subjectHyptis crenatapt_BR
dc.subjectCitotoxidadept_BR
dc.subjectSalva-do-Marajópt_BR
dc.subjectCompostos fenólicospt_BR
dc.subjectSalvaterra - PApt_BR
dc.subjectIlha de Marajó - PApt_BR
dc.subjectPará - Estadopt_BR
dc.subjectAmazônia brasileirapt_BR
dc.titleAntioxidant capacity and biological activity of essential oil and methanol extract of Hyptis crenata Pohl ex Benthpt_BR
dc.title.alternativeCapacidade antioxidante e atividade biológica do óleo essencial e extrato metanólico de Hyptis crenata Pohl ex Benthpt_BR
dc.typeArtigo de Periódicopt_BR
dc.description.resumoO óleo essencial das folhas e ramos finos frescos e secos de Hyptis crenata forneceu os seguintes rendimentos, 1,4% e 0,9%. Os constituintes voláteis principais foram α-pineno (22,0%; 19,5%), 1,8-cineol (17,6%; 23,2%), β-pineno (17,0%: 13,8%), cânfora (4,7%; 11,6%), limoneno (5,4%; 4,4%) e γ-terpineno (3,5%; 2,4%), totalizando mais de 70% nos óleos. A atividade de seqüestro do radical DPPH para o extrato metanólico (CE50, 16,7 + 0,4 µg/mL) foi comparável ao do BHT (19,8 ± 0,5 µg/mL) mostrando uma significante atividade antioxidante. Os óleos apresentaram baixa atividade. O teor de fenólicos totais (TP, 373,0 + 15,9 mg GAE/g) e equivalente trolox (TEAC, 226,8 + 0,5 mg TE/g) confirmaram a atividade antioxidante do extrato metanólico, que pode ser atribuída à presença de compostos fenólicos polares. No teste com larvas de camarão as concentrações letais para o óleo e extrato metanólico foram 6,7 + 0,2 µg/mL e 13,0 + 3,7 µg/mL, respectivamente, fornecendo importante evidência de suas atividade biológicas.pt_BR
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