Avaliação do nível de concordância do teste imunocromatográfico OptiMAL-IT® e a gota espessa no diagnóstico da malária, no município de Mazagão-AP, Brasil

Abstract

The precocious diagnosis and the opportune treatment of the cases of malaria is one of the main strategies for the control of the disease. Several alternatives for the traditional microscopic diagnosis were proposed in the last years, the Immunochromatographic tests that capture white antigens of the parasites of the malaria they are being proposed, as the test OptiMAL-IT® that captures the lactic desidrogenase of the Plasmodium sp.. The study had as objective the evaluation of the level of agreement between the Immunochromatographic test (OptiMAL-IT®) and the thick drop for the diagnosis of the malaria in the City of Mazagão – Amapá, Brazil. 413 individuals were analyzed with malaria sintomatology that had looked for the service of the unit of health service of the city, with age among 01-68 years. The results of the OptiMAL-IT® test were compared with the obtained results, of the same samples, through the thick drop red-faced by the Giemsa. Of the 413 patients suspicious to present malaria, 317(76.8%) were positive through GE and 311 (75.3%) were positive for TDR OptiMAL-IT®. Of the positive blades of GE, had been found 27.4% of P. falciparum and 72.6% of P. vivax . The OptiMAL-IT® test detected 27.7% of P. falciparum and 72.3% of P. vivax. The sensibility obtained with TDR for P. falciparum was of 97.7% and for P. vivax was of 98.2%, the global sensibility of TDR was of 98.1% and the global specificity for both the species was of 100%. They were found preditivos values positive and negative of 100% and 94.1%, respectively. The OptiMAL-IT® test had a high agreement with thick drop, it is specific and efficient. It can be used in the diagnosis of malaria in the situations where microscopy is not available.