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metadata.dc.type: Artigo de Periódico
Issue Date: Apr-2015
metadata.dc.creator: ISHAK, Marluísa de Oliveira Guimarães
COSTA, Maurimélia Mesquita da
ALMEIDA, Núbia Caroline Costa de
SANTIAGO, Angélica Menezes
BRITO, William Botelho de
VALLINOTO, Antonio Carlos Rosário
AZEVEDO, Vânia Nakauth
ISHAK, Ricardo
Title: Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination
Citation: ISHAK, Marluísa de Oliveira Guimarães et al. Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 48, n. 2, p. 170-174, abr. 2015. Disponível em: <>. Acesso em: 15 fev. 2017. <>.
Abstract: INTRODUCTION: Chlamydia infection is associated with debilitating human diseases including trachoma, pneumonia, coronary heart disease and urogenital diseases. Serotypes of C. trachomatis show a fair correlation with the group of diseases they cause, and their distribution follows a well-described geographic pattern. Serotype A, a trachoma-associated strain, is known for its limited dissemination in the Middle East and Northern Africa. However, knowledge on the spread of bacteria from the genus Chlamydia as well as the distribution of serotypes in Brazil is quite limited. METHODS: Blood samples of 1,710 individuals from ten human population groups in the Amazon region of Brazil were examined for antibodies to Chlamydia using indirect immunofluorescence and microimmunofluorescence assays. RESULTS: The prevalence of antibodies to Chlamydia ranged from 23.9% (Wayana-Apalai) to 90.7% (Awa-Guaja) with a mean prevalence of 50.2%. Seroreactivity was detected to C. pneumoniae and to all serotypes of C. trachomatis tested; furthermore, we report clear evidence of the as-yet-undescribed occurrence of serotype A of C. trachomatis. CONCLUSIONS: Specific seroreactivity not only accounts for the large extent of dissemination of C. trachomatis in the Amazon region of Brazil but also shows an expanded area of occurrence of serotype A outside the epidemiological settings previously described. Furthermore, these data suggest possible routes of Chlamydia introduction into the Amazon region from the massive human migration that occurred during the 1,700s.
Keywords: Infecções por Chlamydia
Sorotipo A
Amazônia brasileira
Series/Report no.: Revista da Sociedade Brasileira de Medicina Tropical
ISSN: 0037-8682 Brasil
Publisher: Universidade Federal do Pará
metadata.dc.publisher.initials: UFPA
metadata.dc.rights: Acesso Aberto
Appears in Collections:Artigos Científicos - ICB

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