Use este identificador para citar ou linkar para este item:
https://repositorio.ufpa.br/jspui/handle/2011/7800
Tipo: | Artigo de Periódico |
Data do documento: | Dez-2016 |
Autor(es): | OHASHI, Camila Melo CALDEIRA, Fabio Alves Morikawa FEITOSA JUNIOR, Denilson José Silva VALENTE, André Lopes DUTRA, Paulo Roberto Witter MIRANDA, Moysés dos Santos SANTOS, Simone do Socorro Damasceno BRITO, Marcus Vinicius Henriques OHASHI, Otávio Mitio YASOJIMA, Edson Yuzur |
Título: | Stem cells from adipose tissue improve the time of wound healing in rats |
Citar como: | OHASHI, Camila Melo et al. Stem cells from adipose tissue improve the time of wound healing in rats. Acta Cirúrgica Brasileira, São Paulo, v. 31, n. 12, p. 821-825, Dec. 2016. DOI: http://dx.doi.org/10.1590/s0102-865020160120000007. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/7800. Acesso em:. |
Abstract: | PURPOSE: To evaluate the Adipose Stem Cells (ACS) therapy efficacy on the time and quality of wound healing process in rats. METHODS: Nine male Wistar rats were randomly distributed into three groups I) 7 days of healing; II) 14 days of healing; III) 21 days of healing. Four incisions were made on the dorsal surface of each rat and then treated with intralesional ACS, meloxicam, and no treatment and ACS+meloxicam. Macroscopic evaluation was measured by percentage of healing and histopathological by hematoxylineosin was performed. RESULTS: All groups have the wound reduced during the three weeks (p<0.001) and after 14 days of healing had greater reduction than others. Wounds treated with ASC had accelerated healing in relation to no treatment and only meloxicam (p<0.001), excepting the ASC+Meloxicam that was similar (p=0.13). There was no difference in histopathological analysis between lesions. CONCLUSION: Adipose stem cell have benefits in reducing time of healing of experimental model of wound in rats, observed 7 days of after application. |
Palavras-chave: | Células-tronco Tecido adiposo Cicatrização Histologia Adipose tissue Wound healing Stem cells Rats |
Título do Periódico: | Acta Cirúrgica Brasileira |
ISSN: | 1678-2674 |
País: | Brasil |
Instituição: | Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
Sigla da Instituição: | SOBRADPEC |
Tipo de Acesso: | Acesso Aberto |
Fonte URI: | http://ref.scielo.org/qdbyqx |
Identificador DOI: | http://dx.doi.org/10.1590/s0102-865020160120000007 |
Aparece nas coleções: | Artigos Científicos - ICS |
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Article_StemCellsAdipose.pdf | 609,41 kB | Adobe PDF | Visualizar/Abrir |
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