Use este identificador para citar ou linkar para este item:
https://repositorio.ufpa.br/jspui/handle/2011/8875
Tipo: | Artigo de Periódico |
Data do documento: | Jun-2017 |
Autor(es): | SOUZA, Ronilson Freitas de SILVA, Geilson Alcantara da ARRUDA, Alberto Cardoso SILVA, Milton Nascimento da SANTOS, Alberdan Silva GRISÓLIA, Daniella Paternostro de Araújo SILVA, Moisés Batista da ARRUDA, Mara Silvia Pinheiro |
Título: | A New Prenylisoflavone from the Antifungal Extract of Leaves of Vatairea guianensis Aubl. |
Citar como: | SOUZA, Ronilson Freitas de et al. A New Prenylisoflavone from the Antifungal Extract of Leaves of Vatairea guianensis Aubl. Journal of the Brazilian Chemical Society, São Paulo, v. 28, n. 6, p. 1132-1136, jun. 2017. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532017000601132&lng=pt&nrm=iso>. Acesso em: 18 jul. 2017. <http://dx.doi.org/10.21577/0103-5053.20160250>. |
Abstract: | A new compound, 5,7,3'-trihydroxy-4'-methoxy-8-prenylisoflavone, was isolated from the leaves of Vatairea guianensis Aubl. (Fabaceae), together with two known isoflavones lupiwighteone and 5,7,4'-trihydroxy-3'-methoxy-8-prenylisoflavone. All isolated compounds were characterized based on infrared (IR), UV, 1H and 13C nuclear magnetic resonance (NMR), including 2D NMR analyses and high resolution mass spectrometry. The ethanolic extract from V. guianensis leaves displayed activity against Candida dubliniensis, C. albicans and C. krusei. However, the EtOAc fraction from that extract exhibited more significant activity than the ethanolic extract, showing antifungal activity for all fungi species investigated. The major compound 5,7,3'-trihydroxy-4'-methoxy-8-prenylisoflavone isolated from that EtOAc fraction was also active against C. parapsilosis and C. dubliniensis. |
Palavras-chave: | Antifúngicos Vatairea guianensis Flavonóides Fabaceae Prenilisoflavona |
Título do Periódico: | Journal of the Brazilian Chemical Society |
ISSN: | 1678-4790 |
País: | Brasil |
Instituição: | Universidade Federal do Pará |
Sigla da Instituição: | UFPA |
Tipo de Acesso: | Acesso Aberto |
Aparece nas coleções: | Artigos Científicos - ICEN |
Arquivos associados a este item:
Arquivo | Descrição | Tamanho | Formato | |
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Artigo_NewPrenylisoflavoneAntifungal.pdf | 176,97 kB | Adobe PDF | Visualizar/Abrir |
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