2013-12-112013-12-112011-12BRITO JUNIOR, Lacy Cardoso de et al. Diagnóstico de imunofenótipos de síndromes linfoproliferativas crônicas por citometria de fluxo na Fundação HEMOPA. Jornal Brasileiro de Patolologia e Medicina Laboratorial, Rio de Janeiro, v. 47, n. 6, p. 607-610, dez. 2011. Disponível em: <http://www.scielo.br/pdf/jbpml/v47n6/v47n6a06.pdf>. Acesso em: 06 dez. 2013. <http://dx.doi.org/10.1590/S1676-24442011000600006>.1676-2444https://repositorio.ufpa.br/handle/2011/4519INTRODUCTION: Lymphoproliferative syndromes comprise a heterogeneous group of malignant neoplasias with different clinical behaviors, pathological factors and epidemiological characteristics, whose diagnosis may be based on lymphoid cell morphology observed in peripheral blood. OBJECTIVE: To test the diagnostic feasibility of immunophenotyping by flow cytometry for lymphoproliferative syndromes through the definition of minimal antibody panel. MATERIAL AND METHODS: During the period of July 2008 to July 2010, 47 patients from HEMOPA blood center participated in this study for differential diagnosis of lymphoproliferative syndromes subtypes by flow cytometry. RESULTS: The mean age was 68 years old. There was no statistical difference between genders, and the most frequent subtype of lymphoproliferative syndromes was chronic lymphoid leukemia/small B-cell lymphocytic lymphoma. CONCLUSION: Based on the antibody panel recommended in this investigation, the immunophenotyping method by flow cytometry associated with morphological characterization of peripheral blood samples is a reliable, rapid, feasible, and non-invasive procedure for the diagnosis of chronic lymphoproliferative syndromes.porAcesso AbertoCitometria de fluxoImunofenotipagemNeoplasia hematológicaLinfomaDiagnósticoArtigo de Periódico