2019-04-042019-04-042017-07PASCHOAL JUNIOR, Fernando Mendes et al. Cerebral hemodynamic and metabolic changes in fulminant hepatic failure. Arquivos de Neuro-Psiquiatria, São Paulo, v. 75, n. 7, p. 470-476, jul. 2017. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10868. Acesso em:.1678-4227https://repositorio.ufpa.br/handle/2011/10868Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.Acesso AbertoHepatic insufficiencyIntracranial hypertensionBrain edemaInsuficiência hepaticaHipertenção intracranianaEdema encefálicoArtigo de Periódicohttp://dx.doi.org/10.1590/0004-282x20170076