2016-03-142016-03-142003-12MANZI, Flávio Ricardo et al. Estudo morfológico do efeito radioprotetor da vitamina E (dl-alfa-tocoferil) na reparação tecidual em ratos. Radiologia Brasileira, São Paulo, v. 36, n. 6, p. 367-371, dez. 2003. Disponível em: <http://www.scielo.br/pdf/rb/v36n6/18703.pdf>. Acesso em: 14 mar. 2016. <http://dx.doi.org/10.1590/S0100-39842003000600008>.1678-7099https://repositorio.ufpa.br/handle/2011/7142The purpose of this work was to evaluate the action of the vitamin E as a radioprotective agent in the process of tissue reparation in rats submitted to a surgical procedure, which consisted of a wound done in the fore dorsal area. The animals were divided into five groups: group C (controls) - wound; group VE - previous treatment with vitamin E (90 UI); group IR - wound and irradiation of the borders three days after surgery; group VEIR - previous treatment with 90 UI of the vitamin E and irradiation of the borders three days after the surgery; group OIR - previous treatment with olive oil and irradiation of the borders three days after surgery. The radioprotective effect of the vitamin E was evaluated using hematoxylin-eosin stained specimens in order to identify granulation tissue, at 4, 7, 14 and 21 days after the surgical procedures. The results showed that 6 Gy of electron irradiation with a beam of 6 MeV caused retardation of the tissue repairing process and that vitamin E was effective as a radioprotective agent.porAcesso AbertoEstudo morfológicoVitamina ERadioprotetorProtetores contra radiaçãoRadicais livresRadiação ionizanteArtigo de Periódico