2013-01-142013-01-142004-08SARQUIS, Maria Inez de Moura, et al. Production of L-asparaginase by filamentous fungi. Memória do Instituto Oswaldo Cruz. Rio de Janeiro, v. 99, n.5, p. 489-492, ago. 2004. Disponível em: <http://www.scielo.br/pdf/mioc/v99n5/v99n5a05.pdf>. Acesso em: 10 dez. 2013. http://dx.doi.org/10.1590/S0074-02762004000500005.0074-02761678-8060https://repositorio.ufpa.br/handle/2011/3310L-asparaginase production was investigated in the filamentous fungi Aspergillus tamarii and Aspergillus terreus. The fungi were cultivated in medium containing different nitrogen sources. A. terreus showed the highest L-asparaginase (activity) production level (58 U/L) when cultivated in a 2% proline medium. Both fungi presented the lowest level of L-asparaginase production in the presence of glutamine and urea as nitrogen sources. These results suggest that L-asparaginase production by of filamentous fungi is under nitrogen regulation.engAcesso AbertoAsparaginaseAspergillus tamariiAspergillus terreusFilamentos fungiArtigo de Periódico