Please use this identifier to cite or link to this item: http://repositorio.ufpa.br/jspui/handle/2011/10796
metadata.dc.type: Artigo de Periódico
Issue Date: Dec-2018
metadata.dc.creator: CHAVES, Rosa Helena de Figueiredo
SOUZA, Celice Cordeiro de
FURLANETO, Ismari Perini
TEIXEIRA, Renan Kleber Costa
OLIVEIRA, Carolina Pinheiro de
RODRIGUES, Emanuelle de Matos
SANTOS, Daniel Arthur Santos dos
SILVA, Renata Cunha
PENHA, Nelson Elias Abrahão da
LIMA, Ana Rita de
metadata.dc.description.affiliation: FURLANETO, I. P. Universidade Federal do Pará
Title: Influence of tramadol on functional recovery of acute spinal cord injury in rats
Citation: CHAVES, Rosa Helena de Figueiredo et al. Influence of tramadol on functional recovery of acute spinal cord injury in rats. Acta Cirúrgica Brasileira, São Paulo, v. 33, n. 12, p. 1087-1094,  Dec. 2018. DOI: http://dx.doi.org/10.1590/s0102-865020180120000006. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10796. Acesso em:.
Abstract: Purpose: To evaluate the influence tramadol on functional recovery of acute spinal cord injury in rats. Methods: Ten rats were divided into two groups (n = 5). All animals were submitted by a aminectomy and spinal cord injury at eighth thoracic vertebra. In control group, the rats didn’t receive any analgesic. In tramadol group, the rats received tramadol 4mg/Kg at 12/12h until 5 days by subcutaneous. Animals were following by fourteen days. Was evaluated the Basso, Beattie, Bresnahan scale (locomotor evaluation) and Rat Grimace Scale (pain evaluation) at four periods. Results: There no difference between the groups in locomotor evaluation in all periods evaluated (p>0.05) and in both groups there was a partial recover of function. The tramadol group show a lower pain levels at the first, third and seventh postoperatively days when comparing to the control group. Conclusion: The tramadol as an analgesic agent don’t influence on functional recovery of acute spinal cord injury in rats.
Keywords: Neuralgia
Pain
Analgesics
Rats
Series/Report no.: Acta Cirúrgica Brasileira
ISSN: 1678-2674
metadata.dc.publisher.country: Brasil
Publisher: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
metadata.dc.publisher.initials: SOBRADPEC
metadata.dc.rights: Acesso Aberto
metadata.dc.source.uri: http://ref.scielo.org/ncf8gn
metadata.dc.identifier.doi: http://dx.doi.org/10.1590/s0102-865020180120000006
Appears in Collections:Artigos Científicos - NMT

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