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metadata.dc.type: Artigo de Periódico
Issue Date: Apr-1997
metadata.dc.creator: DINIZ, Domingos Luiz Wanderley Picanço
OLIVEIRA, Gustavo Ribeiro de
FAVARETTO, Ana Lucia Vianna
RODRIGUES, José Antunes
Title: Does plasma ANP participate in natriuresis induced by a-MSH?
Citation: PICANÇO-DINIZ, D.L.W. et al. Does plasma ANP participate in natriuresis induced by a-MSH? Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 30, n. 4, p. 459-463, abr. 1997. Disponível em: <>. Acesso em: 11 dez. 2012. <>.
Abstract: -Melanocyte-stimulating hormone (-MSH; 0.6 and 3 nmol) microinjected into the anteroventral region of the third ventricle (AV3V) induced a significant increase in diuresis without modifying natriuresis or kaliuresis. Intraperitoneal (ip) injection of -MSH (3 and 9.6 nmol) induced a significant increase in urinary sodium, potassium and water excretion. Intraperitoneal (3 and 4.8 nmol) or iv (3 and 9.6 nmol) administration of -MSH did not induce any significant changes in plasma atrial natriuretic peptide (ANP), suggesting that the natriuresis, kaliuresis and diuresis induced by the systemic action of -MSH can be dissociated from the increase in plasma ANP. These preliminary results suggest that -MSH may be involved in a -MSHindependent mechanism of regulation of hydromineral metabolism.
Keywords: Hormônio estimulador de melanócito
Fator natriurético atrial
ISSN: 1414-431X
metadata.dc.rights: Acesso Aberto
Appears in Collections:Artigos Científicos - ICB

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