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Title: Antioxidant capacity and larvicidal activity of essential oil and extracts from Lippia grandis
metadata.dc.creator: DAMASCENO, Evelyn Ivana Trindade
SILVA, Joyce Kelly do Rosário da
ANDRADE, Eloisa Helena de Aguiar
SOUSA, Pergentino José da Cunha
MAIA, José Guilherme Soares
Keywords: Plantas aromáticas
Lippia grandis
Capacidade antioxidante
Atividade larvicida
Amazônia brasileira
Issue Date: Feb-2011
Citation: DAMASCENO, Evelyn Ivana T. et al. Antioxidant capacity and larvicidal activity of essential oil and extracts from Lippia grandis. Revista Brasileira de Farmacognosia, Curitiba, v. 21, n. 1, p. 78-85, jan./fev. 2011. Disponível em: <>. Acesso em: 22 jan. 2013. <>.
Abstract: The leaves and thin branches of Lippia grandis Schauer, Verbenaceae, are used for flavoring of food in the Brazilian Amazon, as substitute for oregano. In this study the constituents of the essential oil were identified and the antioxidant capacity and larvicidal activity of the oil and methanol extract and its sub-fractions were evaluated. A sensory evaluation was determined in view of absence of toxicity. The oil showed a yield of 2.1% and its main constituents were thymol (45.8%), p-cymene (14.3%), γ-terpinene (10.5%), carvacrol (9.9%) and thymol methyl ether (4.8%), totalizing 85%. The DPPH radical scavenging activity showed values for the EC50 between 9.0 and 130.5 µg mL-1 and the TEAC/ABTS values varied from 131.1 to 336.0 mg TE/g, indicating significant antioxidant activity for the plant. The total phenolic content ranged from 223.0 to 761.4 mg GAE/g, contributing to the antioxidant activity observed. The crude extracts inhibited the bleaching of β-carotene and the oil showed the greatest inhibition (42.5%). The oil (LgO, 7.6±2.4 µg mL-1) showed strong larvicidal activity against the brine shrimp bioassay. The sensory evaluation was highly satisfactory in comparison to oregano. The results are very promising for the use of L. grandis in seasoning and antioxidant products.
ISSN: 0102-695X
Appears in Collections:Artigos Científicos - FAQUI/ICEN

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