Please use this identifier to cite or link to this item: http://repositorio.ufpa.br/jspui/handle/2011/4418
metadata.dc.type: Artigo de Periódico
Issue Date: Mar-2013
metadata.dc.creator: BOTELHO, Nara Macedo
CORRÊA, Suelen Costa
LOBATO, Rodolfo Costa
TEIXEIRA, Renan Kleber Costa
QUARESMA, Juarez Antônio Simões
metadata.dc.creator.ORCID: https://orcid.org/0000-0002-5079-297X
https://orcid.org/0000-0002-6267-9966
metadata.dc.description.affiliation: QUARESMA, J. A. S. Universidade Federal do Pará
Title: Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam
metadata.dc.description.sponsorship: FAPESPA - Fundação Amazônia de Amparo a Estudos e Pesquisas
Citation: BOTELHO, Nara Macedo, et al. Immunohistochemistry of the uterine cervix of rats bearing the Walker 256 tumor treated with copaiba balsam. Acta Cirúrgica Brasileira, São Paulo, v. 28, n. 3, p. 185-189, Mar. 2013. DOI: http://dx.doi.org/10.1590/S0102-86502013000300005. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/4418. Acesso em:.
Abstract: PURPOSE: To investigate the immunohistochemistry of the uterine cervix of 20 Wistar rats (Rattus norvegicus) bearing the Walker 256 tumor, treated with copaiba oil (Copaifera officinalis). METHODS: The animals were grouped into four subgroups, with five rats each: the GCT and GCopT received distilled water and topically copaiba, respectively, while the GCG and GCopG received distilled water and copaiba by gavage, respectively. The substances were administered for nine days. On the 12th day, after euthanasia, the tumor pieces were sent to the identification of T CD4+, T CD8+ and Natural Killer cells. RESULTS: It was found that the pattern of expression for specific markers of phenotypes of cells involved in tumor immune response was similar in all groups, regardless the administration way of copaiba oil (topical or gavage). CONCLUSION: Copaiba balsam, administered either topically or by gavage, did not alter the pattern of tumor immune response in rats bearing Walker 256 Tumor.
Keywords: Carcinoma 256 de Walker
Cerclagem cervical
Imunoistoquímica
Copaíba
Immunohistochemistry
Cervix uteri
Rats
Series/Report no.: Acta Cirúrgica Brasileira
ISSN: 1678-2674
metadata.dc.publisher.country: Brasil
Publisher: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
metadata.dc.publisher.initials: SOBRADPEC
metadata.dc.rights: Acesso Aberto
metadata.dc.source.uri: http://ref.scielo.org/qdsjc7
metadata.dc.identifier.doi: http://dx.doi.org/10.1590/S0102-86502013000300005
Appears in Collections:Artigos Científicos - NMT

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