Please use this identifier to cite or link to this item: http://repositorio.ufpa.br/jspui/handle/2011/4553
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Type: Artigo de Periódico
Issue Date: 2013
Authors: PINHEIRO, Eduardo Antonio Abreu
CARVALHO, Josiwander Miranda
SANTOS, Diellem Cristina Paiva dos
FEITOSA, André de Oliveira
MARINHO, Patrícia Santana Barbosa
GUILHON, Giselle Maria Skelding Pinheiro
SANTOS, Lourivaldo da Silva
SOUZA, Afonso Duarte Leão de
MARINHO, Andrey Moacir do Rosário
Title: Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity
Citation: PINHEIRO, Eduardo A. A. et al. Chemical constituents of Aspergillus sp EJC08 isolated as endophyte from Bauhinia guianensis and their antimicrobial activity. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 85, n. 4, p. 1247-1252, 2013, Epub 21 out. 2013. Disponível em: <http://www.scielo.br/pdf/aabc/v85n4/0001-3765-aabc-aop7013.pdf>. Acesso em: 13 dez. 2013. <http://dx.doi.org/10.1590/0001-3765201395512>.
Resumo: Neste trabalho estamos reportando o isolamento de cinco compostos de Aspergillus sp EJC08 isolado como endofítico de Bauhinia guianensis uma planta típica da Amazônia. Os compostos ergosterol (1), peróxido de ergosterol (2), mevalolactona (3), monometilsulocrina (4) e tripacidina A (5) foram isolados através de procedimentos cromatográficos e identificados por métodos espectrais de RMN 1D e 2D e EM. Os compostos 3, 4 e 5 foram testados contra Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis e Staphylococcus aureus e mostraram boa atividade.
Abstract: The present work reports the isolation of five compounds from Aspergillus sp EJC08 isolated as endophytic from Bauhinia guianensis, a tipical plant of the Amazon. The compounds ergosterol (1), ergosterol peroxide (2), mevalolactone (3), monomethylsulochrin (4) and trypacidin A (5) were isolated by chromatographic procedures and identified by spectral methods of 1D and 2D NMR and MS. Compounds 3, 4 and 5 were tested against Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Staphylococcus aureus and showed good activity.
Keywords: Constituintes químicos
Ensaio antimicrobiano
Aspergillus
Bauhinia guianensis
Amazônia Brasileira
ISSN: 0001-3765
Appears in Collections:Artigos Científicos - FAQUI/ICEN

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