Please use this identifier to cite or link to this item: http://repositorio.ufpa.br:8080/jspui/handle/2011/4861
Title: Estudo soroepidemiológico da co-infecção pelo Vírus da hepatite B em portadores do HIV-1 e/ou com SIDA/AIDS no Estado do Amapá
metadata.dc.creator: PORCY, Márcia Socorro Cavalcante
metadata.dc.contributor.advisor1: ISHAK, Ricardo
Keywords: Doenças transmissíveis
HIV (Vírus)
Vírus da hepatite B
Coinfecção
Fatores de risco
Macapá - AP
Amapá - Estado
Amazônia brasileira
Issue Date: 14-Jan-2006
Publisher: Universidade Federal do Pará
Citation: PORCY, Márcia Socorro Cavalcante. Estudo soroepidemiológico da co-infecção pelo Vírus da hepatite B em portadores do HIV-1 e/ou com SIDA/AIDS no Estado do Amapá. 2006. 106 f. Dissertação (Mestrado) – Universidade Federal do Pará, Centro de Ciências Biológicas, Belém, 2006. Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários.
Abstract: Risk factors and forms of transmission for human immunodeficiency virus (HIV) and hepatitis B virus (HBV) are often the same, which explains the high frequency of co-infection involving these two agents. The objective of this investigation was to assess the prevalence of HBV and possible risk factors for this disease as well to examine association between CD4+, CD8+ lymphocytes T count and plasmatic viral load in 129 patients with HIV. Each participant was submitted to a specific questionnaire and had a blood sample tested for the serologic markers HBsAg, total anti-HBc, anti-HBs, CD4+, CD8+ lymphocytes T count and plasma viral load. The overall prevalence of hepatitis B virus infection was 46,5%, with positivity 3,1% for HBsAg, 27,1% for total anti-HBc and 36,4% for anti-HBs. After adjustment using logistic regression, hepatitis B serological markers were associated with the following variables: sex, sexual preference and education level. The frequency of hepatitis B markers was 39,1% in men and 16,6% in women. The prevalence of hepatitis B markers was 14,4% in homo/bisexual and 15,4% in heterosexuals. The lower frequency (1%) of hepatitis B was determined in group of individual with higher education level. No significant statiscally difference was observed between CD4 and CD8 lymphocytes count and plasmatic viral load in the co-infected with HBV compared to that in patients infected only with HIV.
URI: http://repositorio.ufpa.br/jspui/handle/2011/4861
Appears in Collections:Dissertações em Biologia de Agentes Infecciosos e Parasitários (Mestrado) - PPGBAIP/ICB

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