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Title: Epidemiologia e perfil de sensibilidade de Staphylococcus aureus procedentes de hospitais públicos de Macapá-Amapá
metadata.dc.creator: SOUZA, Margarida Maria Machado de
metadata.dc.contributor.advisor1: RIBEIRO, Karla Tereza Silva
Keywords: Doenças transmissíveis
Staphylococcus aureus
Staphylococcus aureus resistente a oxacilina
Perfil de suscetibilidade
Hospitais públicos
Macapá - AP
Amapá - Estado
Amazônia brasileira
Issue Date: 13-Dec-2007
Publisher: Universidade Federal do Pará
Citation: SOUZA, Margarida Maria Machado de. Epidemiologia e perfil de sensibilidade de Staphylococcus aureus procedentes de hospitais públicos de Macapá-Amapá. 2007. 71 f. Dissertação (Mestrado) – Universidade Federal do Pará, Instituto de Ciências Biológicas, Belém, 2007. Curso de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários.
Abstract: Amongst the Staphylococcus genus, the oxacillin-resistant Staphylococcus aureus is without doubts some the pathogen of bigger importance, when associated to the nosocominal infections, being responsible for high mortality and morbidity rates. This study describes the epidemiology and the sensitivity profile of the Staphylococcus aureus originated from public hospitals of Macapá-Amapá. All strains used in this study had been again isolated through manual and automatized methodology. The oxacilin-resistant samples had all been submitted to the screening test with cefoxitin 30 mcg. The statistical treatment of the data revealed the predominance of the masculine sex (62,8%), being of 20 years the average age of the patients. The biggest occurrence was in the age group of 0 to 10 years, the hospital of bigger prevalence was the Hospital of the Child and the Adolescent (54,7%). The prevalence of the isolated samples in the hosptals was 3,8%. 25 (23,8) of the total isolated samples (n=105) were resistant to oxacilin. These samples presented crossed resistnce to gentamycin (80%), sulfazotrim (72%), tetracyclin (64%), erythromycin (60%), clindamycin (44%), norfloxacin (44%) and quinupristin/dalfopristin (32%). The vancomycin presented 100% of sensitivity. Despite many studies done in Brazil and in the world show high rates of oxacillin-resistant S. aureus, in this research the resistance levels of the bacterium in the public hospitals of Macapá still can be considered low. However, the results reveal the need for systematic surveillance for the control and prevention of the spread of resistant strains of the pathogen associated with nosocomial infection.
Appears in Collections:Dissertações em Biologia de Agentes Infecciosos e Parasitários (Mestrado) - PPGBAIP/ICB

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