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Title: Soroepidemiologia de Chlamydia trachomatis, Chlamydia pneumoniae e Treponema pallidum em portadores do Vírus da imunodeficiência humana (HIV), no Estado do Pará
metadata.dc.creator: ALMEIDA, Núbia Caroline Costa de
metadata.dc.contributor.advisor1: ISHAK, Marluísa de Oliveira Guimarães
Keywords: Doenças transmissíveis
Chlamydia trachomatis
Treponema pallidum
Chlamydophila pneumoniae
HIV (Vírus)
Pará - Estado
Amazônia brasileira
Issue Date: 28-Apr-2009
Publisher: Universidade Federal do Pará
Citation: ALMEIDA, Núbia Caroline Costa de. Soroepidemiologia de Chlamydia trachomatis, Chlamydia pneumoniae e Treponema pallidum em portadores do Vírus da imunodeficiência humana (HIV), no Estado do Pará. 2009. 169 f. Dissertação (Mestrado) – Universidade Federal do Pará, Instituto de Ciências Biológicas, Belém, 2009. Programa de Pós-Graduação em Biologia de Agentes Infecciosos e Parasitários.
Abstract: Chlamydia trachomatis and Treponema pallidum share the sexual route of transmission with HIV-1. In consequence of the compromise of the immune response among HIV-1 carriers, C. pneumoniae is a potential harassment in respiratory infections. The present study intended the description of the seroprevalence of those three agents among 430 HIV-1 infected persons residing in the State of Para, Brazil, attended at the State Reference Unit (URE-DIPE), between September 2007 to June 2008. Plasma samples were tested using an enzyme immuno assay for the detection of IgM and IgG antibodies to Chlamydia and those which elicited positive results were ramdomly selected for serotyping through a microimmunofluorescence assay. Antibodies to T. pallidum were detected using a flocculation reaction (RPR) and an enzyme immunoassay. Results were compared statistically using the Chi square test (χ2). The general prevalence to Chlamydia was 64.2% (51.6% IgG reactivity and 4% to IgM). Serotyping showed 100% reactivity to C. trachomatis (for both IgG and IgM), a high prevalence to C. pneumoniae (73.5% IgG and 70.5% to IgM) and a large distribution of reactivity to strains of C. trachomatis which cause genital infections. Prevalence of antibodies to T. pallidum was 34.9% and 7.3% showed laboratory evidence of syphilis. Infection with both pathogens were associated to several characteristics which included: higher prevalence among males, high age, low number of study years, high number of sexual partners, anal sexual relations, homosexual/bisexual habits, use of non injecting drugs and the history of sti. It is necessary not only the individual attention for prevention, but also the continuous monitoring to block transmission and the improvement of the well being of HIV-1 infected persons.
Appears in Collections:Dissertações em Biologia de Agentes Infecciosos e Parasitários (Mestrado) - PPGBAIP/ICB

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