Please use this identifier to cite or link to this item: http://repositorio.ufpa.br:8080/jspui/handle/2011/5152
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dc.creatorLOOPUIJT, L.D.-
dc.creatorSILVA FILHO, Manoel da-
dc.creatorHIRT, B.-
dc.creatorVONTHEIN, R.-
dc.creatorKREMERS, Joannes Jozef Marie-
dc.date.accessioned2014-06-26T13:29:08Z-
dc.date.available2014-06-26T13:29:08Z-
dc.date.issued2007-10-
dc.identifier.citationLOOPUIJT, L.D. et al. Dendritic thickness: a morphometric parameter to classify mouse retinal ganglion cells. Brazilian Journal of Medical and Biological Research, Ribeirão Preto, v. 40, n. 10, p. 1367-1382, out. 2007. Disponível em: <http://www.scielo.br/pdf/bjmbr/v40n10/6507.pdf>. Acesso em: 20 fev. 2014. <http://dx.doi.org/10.1590/S0100-879X2006005000161>.pt_BR
dc.identifier.issn1414-431X-
dc.identifier.urihttp://repositorio.ufpa.br/jspui/handle/2011/5152-
dc.description.abstractTo study the dendritic morphology of retinal ganglion cells in wild-type mice we intracellularly injected these cells with Lucifer yellow in an in vitro preparation of the retina. Subsequently, quantified values of dendritic thickness, number of branching points and level of stratification of 73 Lucifer yellow-filled ganglion cells were analyzed by statistical methods, resulting in a classification into 9 groups. The variables dendritic thickness, number of branching points per cell and level of stratification were independent of each other. Number of branching points and level of stratification were independent of eccentricity, whereas dendritic thickness was positively dependent (r = 0.37) on it. The frequency distribution of dendritic thickness tended to be multimodal, indicating the presence of at least two cell populations composed of neurons with dendritic diameters either smaller or larger than 1.8 µm ("thin" or "thick" dendrites, respectively). Three cells (4.5%) were bistratified, having thick dendrites, and the others (95.5%) were monostratified. Using k-means cluster analysis, monostratified cells with either thin or thick dendrites were further subdivided according to level of stratification and number of branching points: cells with thin dendrites were divided into 2 groups with outer stratification (0-40%) and 2 groups with inner (50-100%) stratification, whereas cells with thick dendrites were divided into one group with outer and 3 groups with inner stratification. We postulate, that one group of cells with thin dendrites resembles cat ß-cells, whereas one group of cells with thick dendrites includes cells that resemble cat a-cells.pt_BR
dc.language.isoengpt_BR
dc.rightsAcesso Aberto-
dc.subjectCélulas ganglionais da retinapt_BR
dc.subjectMorfologia dentríticapt_BR
dc.subjectInjeção intracelular de neutrotraçadorespt_BR
dc.subjectRetinapt_BR
dc.titleDendritic thickness: a morphometric parameter to classify mouse retinal ganglion cellspt_BR
dc.typeArtigo de Periódicopt_BR
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