Please use this identifier to cite or link to this item: http://repositorio.ufpa.br/jspui/handle/2011/6164
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Type: Artigo de Periódico
Issue Date: Dec-2011
Authors: AGUIAR, Délia Cristina Figueira
BARROS, Vera Lúcia Reis Souza de
PEREIRA, Washington Luiz Assunção
LOIOLA, Rosane do Socorro Pompeu de
MATOS, Gyselly de Cássia Bastos de
VALSECCHI, João
CORVELO, Tereza Cristina de Oliveira
Title: Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
Citation: AGUIAR, Délia Cristina Figueira et al. Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 106, n. 8, p. 936-941, dez. 2011. Disponível em: <http://www.scielo.br/pdf/mioc/v106n8/07.pdf>. Acesso em: 12 dez. 2014. <http://dx.doi.org/10.1590/S0074-02762011000800007>.
Abstract: The histo-blood group ABH antigens were first described in humans. These antigens are only present on erythrocytes from great apes and humans, while in more primitive animals they are found in tissues and body fluids. The ABH antigens are mainly distributed in tissues exposed to the external environment and potentially serve as ligands for pathogens or inhibitors of tissue connections. The objective of this paper was two-fold: (i) to determine the presence of Helicobacter sp. in the gastric mucosa of 16 captive and 24 free-living New World monkeys and (ii) to evaluate the presence of histopathological alterations related to bacterial infection and the associated expression of ABH antigens in the tissue. Stomach tissues from 13 species of monkey were assessed using haematoxylin-eosin and modified Gram staining (Hucker) methods. An immunohistochemical analysis of the tissue revealed the presence of infectious bacteria that were characteristic of the genus Helicobacter sp. The results demonstrate that various species of monkey might be naturally infected with the Helicobacter sp. and that there is an increased susceptibility to infection. This study serves as a comparative analysis of infection between human and non-human primates and indicates the presence of a new species of Helicobacter.
Keywords: Primata
Helicobacter
Infecções por Helicobacter
Imunoistoquímica
ISSN: 0074-0276
Appears in Collections:Artigos Científicos - ICB
Artigos Científicos - FAMED/ICS

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