Artigos Científicos - FANUT/ICS
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Navegando Artigos Científicos - FANUT/ICS por Assunto "Anemia"
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Item Acesso aberto (Open Access) Anemia em gestantes brasileiras antes e após a fortificação das farinhas com ferro(Universidade Federal do Pará, 2011-12) FUJIMORI, Elizabeth; SATO, Ana Paula Sayuri; SZARFARC, Sophia Cornbluth; VEIGA, Gloria Valeria da; QUEIROZ, Valterlinda Alves de Oliveira; COLLI, Célia; ARAUJO, Regilda Saraiva dos Reis Moreira; ARRUDA, Ilma Kruze Grande de; UCHIMURA, Taqueco Teruya; BRUNKEN, Gisela Soares; YUYAMA, Lucia Kiyoko Ozaki; MUNIZ, Pascoal Torres; PRIORE, Silvia Eloiza; TSUNECHIRO, Maria Alice; FRAZÃO, Andréa das Graças Ferreira; PASSONI, Cynthia R Matos Silva; ARAÚJO, Claudia Regina Marchiori AntunesOBJECTIVE: To compare prevalence of anemia and hemoglobin (Hb) levels in Brazilian pregnant women before and after fl our fortifi cation with iron. METHODS: A repeated cross-sectional panel study of public health care centers of municipalities in the five Brazilian regions was conducted. Retrospective data were obtained from 12,119 medical records of pregnant women distributed in two groups: before fortifi cation (delivery prior to June 2004) and after fortifi cation (date of last period after June 2005). Anemia was defi ned as Hb<11.0 g/dl. Hb levels according to gestational age were assessed using two references from the literature. Statistical analysis was carried out using chi-squared tests, Student’s t tests, and logistic regression, with a signifi cance level of 5%. RESULTS: In the total sample, prevalence of anemia fell from 25% to 20% after fortifi cation (p<0.001). However, important regional differences were evident: while signifi cant reductions were seen in the Northeast (37% to 29%) and North (32% to 25%) regions, where pre-fortifi cation prevalence was high, smaller reductions were seen in the Southeast (18% to 15%) and South (7% to 6%) regions, where prevalence was low. Hb levels according to gestational age were slightly higher in the fi rst months of pregnancy and lower after the third or fourth months, depending on the reference used. Logistic regression analysis showed that group, geographic region, marital status, trimester of pregnancy, initial nutritional status, and prior pregnancy were associated with anemia (p<0.05). CONCLUSIONS: Prevalence of anemia decreased after fortifi cation, but remains high in the North and Northeast regions. Although fortifi cation may have played a role in this favorable outcome, the contribution of other public policies implemented during the studied period should also be considered.Item Acesso aberto (Open Access) Impacto da farinha de mandioca fortificada com ferro aminoácido quelato no nível de hemoglobina de pré-escolares(Universidade Federal do Pará, 2003-03) TUMA, Rahilda Conceição Ferreira Brito; YUYAMA, Lucia Kiyoko Ozaki; AGUIAR, Jaime Paiva Lopes; MARQUES, Hedylamar OliveiraObjective: The impact of the cassava flour fortified with iron amino acid chelate was evaluated in 80 pre-scholars of a Philanthropic Unit of Manaus, state of Amazonas, randomly distributed in four groups of 20 children each, for a period of 120 days. Methods: Cassava flour was used without fortification (group zero) or fortified with 1, 2 and 3mg of Fe/day, corresponding respectively to 5, 10 and 15g of flour/day, which were given to the children at lunch time on weekdays. The equivalent amount was previously distributed to their families for flour intake also during the weekends. In the beginning and at the end of the experiment the children’s nutritional status was evaluated, being adopted the cutoff point <-2 Z-scores as a discriminating limit between eutrophy/ malnutrition, in agreement with the World Health Organization criteria, as well as being established as a cutoff point for the occurrence of iron deficiency anemia a hemoglobin rate of less than 11g/dL. Results: At the end of this study, children recovered from chronic malnutrition, and a significant increase (p <5%) of the hemoglobin rates, independently of iron concentration, from 11.4±0.9g/dL to 12.2±0.8g/dL, was observed in all individuals. The formerly anemic children who received cassava flour fortified with 2mg of Fe/day were fully recovered at the end of the research, demonstrating a good performance of this group in relation to the others. Conclusion: A double-blind study is suggested for the consolidation of the recommendation of cassava flour fortified with iron in the prevention of iron deficiency anemia in pre-scholars of the Amazon region.