Navegando por Assunto "Candida"

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Acesso aberto (Open Access)
Avaliação do efeito antifúngico do óleo resina e do óleo essencial de copaíba (Copaifera multijuga Hayne)
(2011) DEUS, Ricardo Jorge Amorim de; ALVES, Claudio Nahum; ARRUDA, Mara Silvia Pinheiro
Copaifera multijuga Hayne oil in natura and its fractions were evaluated as to their fungitoxic activities against five filamentous fungus species belonging to the genus Aspergillus and three yeast species of the genus Candida. Oleoresin and essential oil concentrations ranging from 0.08 mg mL-1 to 1.6 mg mL-1 were used for qualitative and quantitative analyses. The samples were placed onto 5mm-diameter paper discs distributed on Sabouraud's medium in Petri dishes inoculated with spores of the microorganisms and incubated at 28ºC for 10 days. A solution containing 1.6 mg mL-1 miconazole nitrate was used as positive control. Qualitative results showed that the oleoresin presented good activity, while a fraction of the essential oil was highly effective against Candida parapsilosis IOC-2882, Aspergillus flavus IOC-3874 and A tamarii IOC-187 with 16.0±1.4 mm, 19.5±2.1 mm and 12.5±3.5 mm inhibition halos, respectively. The quantitative evaluation showed that 0.3 mg mL-1 oleoresin inhibited the growth of Aspergillus flavus and Candida parapsilosis, while 0.08 mg mL-1 of the essential oil fraction reached this same activity.
Acesso aberto (Open Access)
Avaliação do estado secretor ABH e Lewis em mulheres não grávidas com e sem risco de desenvolver vulvovaginite por Candida sp
(Universidade Federal do Pará, 2003) CARNEIRO, Ligia Maia; CORVELO, Tereza Cristina de Oliveira; http://lattes.cnpq.br/7253864056606024
Na epidemiologic study of Candida sp infection prevalence in non-pregnant women was performed in a population of the north of Brazil (Belem-Pa, 2002). This paper aims to contribute to clear up the infection mechanisms of Candida sp and its possible association to ABO and Lewis group blood antigens and ABH substances secretory status. Such paper comprehended a total of 165 women admitted at the out-patient clinic of "Hospital da Policia Militar" and "Laboratorio de Analises Clinicas do Centro de Ciencias Biologicas da Universidade Federal do Para", who came to those units to undergo gynaecologic examinations, where blood, salive and vaginal mucus samples were taken. Candida sp infection presence was determined through the examination of fresh vaginal secretion and bacterioscopy of vaginal secretion. The identification of ABH and Lewis phenotipes in the blood was determined through direct hemaglutination tests and, in the salive, by Elisa Dot-blot. It was performed a standard form for the obtaining of epidemiologic information. Candida sp prevalation was 47.9%. Among the most commom signals and symptoms associed to Candida sp infections are pruritus and gleet. Women under 40 who did not use condoms and who have already had previous infections presented a higher risk of vulvo-vaginal infection caused by Candida sp. Infected and non-infected women with Candida sp had similar distribuition to the phenotypes of ABO, Lewis blood groups and ABH substances secretory status. And, comparing the expressions of Lewis antigens in the blood, save and vaginal mucus, it was verified that both secretions expressed Lewis antigens without any close relationship to erithrocitic Lewis phenotypes. In such context, it is considered that the nature of genetics diversity in the interaction between Candida sp and host requires more studies involving the identification of different types to determine their probable associations among ABH and Lewis blood groups phenotypes with cadidiasis.