Navegando por Assunto "Equinococose"

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Acesso aberto (Open Access)
Equinococose neotropicial: um estudo anatomopatológico para auxílio em uma sistematização diagnóstica correlacionada a morfologia
(Universidade Federal do Pará, 2012) ABREU JUNIOR, José Maria de Castro; SOARES, Manoel do Carmo Pereira; http://lattes.cnpq.br/1483308844442427; BATISTA, Evander de Jesus Oliveira; http://lattes.cnpq.br/2206444845201080
Equinococcosis is a disease caused by cestodes of the Echinococcus genus, that can be found at the small intestin of animals like bush-dog and domestic dog. Men behave as an accidental host by the ingestion of eggs of the parasite. The larval forms mainly develop at the liver, and sometimes at the lung, causing a cronic diesease that can be easily mistaken by neoplasias. At the State of Pará, North Brazil, there is a great number of cases of this rare diesease, related to Echinococcus vogeli in the Amazon.This study describes six new cases, five in the the liver, and one at the lung, making description a about the kind of inflammatory cells. Fibrosis, giant-cells, calcification and the laminated layer with the typical cerebroid pattern. Rostellar hooklets did not were found. The laminated layer, is not enough to describe the species of Echinococcus, but allows to consider that the worm´s gender is Echinococcus. Even though the number of cases is too small for a statistical analysis, were observed cells that can justify why the disease has a cronic evolution. More works like this, adding more cases are important, because equinococcosis is a neglected diesese.
Acesso aberto (Open Access)
Equinococose policística na Amazônia oriental brasileira: atualização da casuística
(Universidade Federal do Pará, 2004) SOARES, Manoel do Carmo Pereira; SILVA, Carlos Augusto Moreira; ALVES, Max Moreira; NUNES, Heloisa Marceliano; AMARAL, Ivanete do Socorro Abraçado; MÓIA, Lizomar de Jesus Maués Pereira; CONDE, Simone Regina Souza da Silva; CUNHA, Fernanda Barbosa de Almeida da; SILVA, Rosângela Rodrigues; CRESCENTE, Jose Angelo Barletta
By means of epidemiological and clinical-laboratorial approaches was consolidated an update of polycystic echinococcosis in the Eastern Brazilian Amazon, period from 1962 to 2003, including unpublished cases and those already published. In that way, they were identified 40 cases of the disease in referred period, understanding cases coming from the States of Pará and Amapá, Brazil. The width of the ages went from 10 to 72 years and 47,5% belonged to the masculine sex. The liver was the attacked organ (82,5% of the cases). The Echinococcus vogeli (Rausch and Bernstein, 1972), comes as the main agent involved. Starting from the recognition of the importance and of the implications of the handling of the echinococcosis for the tropical area, it is believed that should happen an improvement of the diagnosis, appropriate treatment and of a better registration of the disease.
Acesso aberto (Open Access)
Hidatidose policística no Estado do Acre: contribuição para o diagnóstico, tratamento e prognóstico dos pacientes
(Universidade Federal do Pará, 2010-06) SIQUEIRA, Nilton Ghiotti de; PÓVOA, Marinete Marins; http://lattes.cnpq.br/2256328599939923
The echinococcosis is a zoonosis whose etiological agents are nematodes of the genus Echinococcus. There are five species of Echinococcus, two of them, E. oligarthrus (Diesing, 1863) and E. vogeli (Rausch & Bernstein, 1972) only occur in neotropical areas. The echinococcosis by E. vogeli causes multiple hydatid cysts, mainly in the liver of intermediate hosts, of which one is the human being. The lack of knowledge about the disease makes the diagnosis is delayed or even misleading. The lack of systematic information on treatment is also difficult to assess the results and prognosis of patients with peritoneal and hepatic lesions caused by E. vogeli. Here we describe the clinical features of patients, we propose a radiological classification protocol used in the classification of alveolar echinococcosis (E. multilocularis "PNM" Classification, Kern et al., 2006), which was also suitable for polycystic echinococcosis (E. vogeli) and describe a therapeutic option for the treatment of hydatid disease which previously had only been used for cases of cystic echinococcosis (E. granulosus, PAIR-Puncture, Aspiration, Injection, Reaspiration, Brunnetti et al., 2001). A prospective cohort study was initiated in 1999 and by 2009 included 60 patients. We describe the main symptoms and signs: pain in upper abdomen (65%) and hepatomegaly (60%) and patients were classified according to the "PNM" classification and submitted to three therapeutic modalities: (i) chemotherapy with albendazole at a dose of 10mg/kg/day, (ii) surgical removal of cysts or (iii) percutaneous puncture of the cysts- PAIR. After exclusion of two cases, due to inadequacy of the research protocol, the groups were distributed as follows: treatment with albendazole: n = 28 (48.3%, 28/58), surgical therapy: n = 25 (52.1%; 25/58) and PAIR: n = 5 (8.1%, 5 / 58). The results were stratified according to outcome of therapy: "Cure", represented by the disappearance of lesions after clinical or surgical treatment, "clinical improvement", defined as asymptomatic patients without weight loss and physiological functions preserved, "No Improvement" included patients who remained symptomatic, "Death" and "No Information", the monitoring did not allow a conclusion about the outcome. The three treatment groups together demonstrade lethality rate of 15.5% (9 / 58), "no improvement" 1.7% (1 / 58), "clinical improvement" in 40.0% (23/58) and "cure "in 32.8% (19/58). Regarding the outcome "death", there was no difference between therapies with albendazole or surgical treatment with 4 (14.2%) and 3 (12%) deaths respectively, but in the first group, albendazole, the outcome "cure" was 4.3% (1 / 23) and "clinical improvement" 74.0% (17/23), whereas in the "surgery" to "cure" represented 71.0% (17/24) and "clinical improvement" 16.7 (4 / 24). Therapy "PAIR" was associated with a lethality rate of 40% (2 / 5), cure in 20% (fifth) and clinical improvement in 40% (2 / 5). The "PNM" classification was useful to indicate such therapy in cases of polycystic hydatid disease. In conclusion, in the series studied surgical therapy has better results in the clinical therapy on the outcomes "cure" and "clinical improvement". The treatment for PAIR needs further studies.