Navegando por Assunto "Medicinal plants"

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Acesso aberto (Open Access)
Atividade citoprotetora e cicatrizante da espécie Conocarpus erectus l em lesões gástricas induzidas em ratos Wistar adultos
(Universidade Federal do Pará, 2017-09-06) VIEIRA, Vaneza Rodrigues; MELLO, Vanessa Joia de; http://lattes.cnpq.br/9437589201689717
The pharmacological research has been aimed at the knowledge of regional folk medicine, in order to establish the scientific bases of their respective pharmaceutical products’ effectiveness. Among the many natural sources used in our region are the species Conocarpus erectus L, popularly known as the "mangrove bud", belonging to the Combretaceae family. Different parts of the plant such as leaves, stems, fruits and flowers have their biological activity studied, among them the anticancer and antimicrobial effects. Ethnopharmacological reports obtained in the region of Salinópolis - PA also described a potential use in digestive disorders. Although a great advance in the drug therapy used in the cases of gastric ulcerationhas been made, it is important to carry out studies that prove its validity. This work aims to verify the cytoprotective activity and cicatrizing activity of the lyophilisatebark teaobtained by decoction of the species Conocarpus erectus L (LCE) in acute and chronic gastric lesions. The methodologies for evaluating the cytoprotective effect were acute lesions inducted by indomethacin and ethanol, while the cicatrization effect was evaluated by chronic acetic acid-induced lesions in adult Wistar rats. The intragastric pH variation was measured by the pylorus ligament assay. The lyophilizate’santioxidant activity was evaluated by the DPPH assay, as well as the lipid perioxide levels’ that were evaluated by the TBA-RS method in chronic lesions induced by acetic acid 5 and 10%. The results showed cytoprotective activity of LCE by the indomethacin induction model reduced the ulceration index (IU) in the treated group by 51,49%, omeprazole group by 51,33% and sucralfate group by 71,28%, all of them when compared to the controlled group. On the model of ethanol LCE’s induction, the area affected was reduced by 90.94%, and in the sucralfate’s induction group, by 75.88% when compared with the controlled group. The LCE’s healing effect reduced gastric lesions to 5% in 80.11%, while the on omeprazole group to 52.75% and the sucralfate group reduced to 66.33%, whereas in the 10% gastric lesionsthe LCE group reduced 72.11%, the omeprazole 57.47%, and the sucralfate group 43.77% (p>0,05Anova, post testDunnett'sand Turkey). The LCE treatment showed an increase of 39% onintragastric pH when compared to control (p>0,05Anova, post testDunnett's e Turkey’s) and did not statistically showed any different from the omeprazole group by the model of pylorus ligation. The LCElyophilizate’santioxidant effect was confirmed by the DPPH assay, as it was diluted in 10x, 50x and 100x with a percentage of 67.65% ± 0.52, 73.22% ± 0.17 and 72.70% ± 1.39, respectively, when compared to the ascorbic acid antioxidant of 33,74% (AA) like this (p <0.05, Anovapost testDunnett). A lipid peroxidation evaluated in the lesions obtained by the 5%-acetic-acid-induction model showed that the average MDA levels in the nave group, controlled group and treated group LCE were 0.492 ± 0.0849, 1.579 ± 0.219, and 0.399 ± 0.092, respectively, showing that the LCE-treated group was able to reduce lipid peroxidation by 74.73% in comparison to the controlled group (p<0,05 Anovapost testDunnet) and it did not statisticallydiffer from the nave group. On the 10%-acetic-acid-model the average level of malonaldehyde in the nave group, controlled group and the LCE-treated group was 0.628 ± 0.042, 1.567 ± 0.234 and 0.441 ± 0.12, respectively. The LCE treated group managed to reduce by 71.85% the lipid peroxidation caused by acetic acid induced lesions when compared to the control group (p <0.05 Anovapost testDunnet).These results confirm the cytoprotective and cicatrizing effects of LCEand suggest possible action mechanisms associated with its antioxidant potential, as well as possible acid secretion inhibition.
Acesso aberto (Open Access)
Boas práticas na produção de fitoterápicos artesanais: estudo de caso no grupo erva vida de Marapanim, estado do Pará-br.
(Universidade Federal do Pará, 2023-12-14) LEAL, Felipe Salomão Valente; LOPES, Luis Otávio do Canto; http://lattes.cnpq.br/1013147545099173; https://orcid.org/0000-0002-6209-9646; BARBOSA, Wagner Luiz Ramos; http://lattes.cnpq.br/1372405563294070; https://orcid.org/0000-0002-2421-8245
In a multicultural country like Brazil, with an extensive and diverse flora, different specific human groups still prepare artisanal herbal medicines based on predominantly empirical knowledge such groups are considered to possess the necessary wisdom for this purpose. These communities apply this wisdom as an effective and accessible alternative to treat their illnesses, associating it with medicinal plants. Despite being ancient, phytotherapy is still actively expanding in modern society, considering the significant need for more accessible therapeutic options. However, to guarantee the quality and safety of these herbal medicines produced by hand, procedures that reflect Good Manufacturing Practices (GMP) are necessary. Thus, the general objective of this work was to understand the regulation of herbal medicine production to propose adequate and appropriate operational procedures for the qualified production of artisanal herbal medicines by community organizations. To this end, a case study was carried out with the Erva Vida group in Marapanim/PA to understand the knowledge involved in the artisanal production of herbal medicines. Bibliographical research was performed to understand, analyze, and interpret the official regulations and to evaluate the elements contained in the regulatory instruments for good production practices that can be introduced in the manufacture of herbal medicines by the community adapting it without distorting the artisanal nature of the process. After these steps and, based on the results obtained, two technological products were developed and proposed as guidance instruments: the “Roadmap for evaluating the hygienic-sanitary conditions of good manufacturing practices in the artisanal production of herbal medicines” more technical, and the “Printbook for the application of Good Manufacturing Practices in artisanal production establishments of artisanal herbal medicines” with more didactic characteristics. The first product was applied to the Erva Vida group, and the results were quantified and subsequently analyzed qualitatively to construct the second product. Finally, implementing elements of good manufacturing practices is proposed to contribute to the continuity and traditionality of this production, incorporating elements that can make its products safer and more effective without eroding the cultural characteristics of the artisanal production group.
Acesso aberto (Open Access)
Ethnoveterinary knowledge of the inhabitants of Marajó Island, Eastern Amazonia, Brazil
(Instituto Nacional de Pesquisas da Amazônia, 2011) MONTEIRO, Maria Vivina Barros; BEVILAQUA, Claudia Maria Leal; PALHA, Maria das Dores Correia; BRAGA, Roberta Rocha; SCHWANKE, Katiane; RODRIGUES, Silvane Tavares; LAMEIRA, Osmar Alves
There have been ethnoveterinary reports from around the world investigating plant usage in therapeutic protocols; however, there is no information regarding the ethnoveterinary practices in Brazilian Amazonia. The objective of this work was to register and document the ethnoveterinary knowledge of the inhabitants of the Island of Marajó, eastern Amazonia, Brazil. In the study, interviews were conducted with 50 individuals, with the application of semi-structured questionnaires that were quantitatively analyzed using descriptive statistic methods of frequency distribution. Use-value was calculated to determine the most important species. Samples of plants that were reported to have medicinal value were collected and identified by botanical classification. Fifty plants, distributed among 48 genera and 34 families, were indicated for 21 different medicinal uses. The family Asteraceae had the largest number of reported species; Carapa guianensis Aubl., Copaifera martii Hayne, Crescentia cujete L., Caesalpinia ferrea Mart., Chenopodium ambrosioides L., Jatropha curcas L. and Momordica charantia L. were species with highest use- value. The plant parts that were more commonly utilized for the preparation of ethnoveterinary medicines were the leaves (56%), bark (18%), roots (14%), seeds (14%) and fruit (8%). With regard to usage, tea was reported as a usage method by 56% of the informants; most preparations (90.9%) utilized only a single plant. In addition to medicinal plants, informants reported using products of animal and mineral origin. The present study contributed to the construction of an inventory of Marajó Island's ethnoveterinary plants, which might be the basis for future scientific validation studies.
Acesso aberto (Open Access)
Poranduba: uma experiência docente pela sabedoria das plantas medicinais nos rios da Amazônia
(Universidade Federal do Pará, 2024-02-02) Santos, Dioemili Sá dos; Raposo, Elinete Oliveira; http://lattes.cnpq.br/6737474841439654; https://orcid.org/0000-0001-8995-0296
This is a qualitative study, transformed into an (auto)biographical account, based on my experiences as a teacher of 5th grade students in a riverside school in the municipal public network of Ponta de Pedras, Pará, Brazil. The aim was to show the teaching and learning experiences of a teacher and her students in the process of developing a Didactic Sequence (DS) based on ethnobotany in 5th grade science classes. The research was conducted using my training diary and the students' diaries, with records of class activities, semi-structured interviews, photographic records and others. I used Textual Discourse Analysis (TDA) as a methodology for analyzing the empirical material and, after a process of immersion, I systematized two thematic axes of analysis: i) TEA FOR WHAT? An approach with medicinal plants in the early years in a riverside school in the Amazon, and ii) ETNOBOTANICS THROUGH THE GARDENS OF DECOLONIALITY: sowing seeds for (re)thinking teacher training in science.. The results and discussions were presented in two articles, which allow for discussions and reflections on the roles of the teacher and student in these processes, especially regarding the use of ethnobotany in the classroom. It is possible to consider that the teaching proposal has premises for a Decolonial Approach in science teaching, provides meaningful learning, Intercultural Scientific Literacy with valorization traditional knowledge and contributing to citizen education. As a result of this study, I have made available a book in digital format (ebook), called BEYOND TEA: ethnobotany through medicinal plants, which introduces teachers and students to new ways and simple possibilities of teaching and learning botany, culture and science education. These innovative experiences in science teaching are easy to apply and replicate in everyday school life, and can be reframed by teachers according to the needs of each class.
Acesso aberto (Open Access)
Processo de estabelecimento de cultivo in vitro de plântulas de simaba cedron planch (simaroubaceae)
(Universidade Federal do Pará, 2020-11-16) LIRA, Marcia Santos de Freitas; LEITE, Jandecy Cabral; http://lattes.cnpq.br/7279183940171317
Simaba cedron, popularly known as "cedron", is largely used for fever and snake bites. Its seeds are used in the treatment of stomach problems and liver infections. The fruits are used for the treatment of pain and malaria while its bark is an antispasmodic. Simaba cedron is generally propagated through seeds, but with limited success, as the low viability of same restricts its propagation. In view of such difficulty, it becomes necessary the study for adequate conditions for the large-scale production of these seedlings. Being it known that in several species, the use of micropropagation has made it possible to obtain a large amount of disease-free and more homogeneous seedlings, in reduced time and physical space, in comparison with conventional propagation methods, the objective of this work was to analyze the effect of two culture media on the production of aseptic parent plants as a first step in the development of a micropropagation protocol for Simaba cedron. The seeds were collected from a matrix plant located in the Centro de Biotecnologia da Amazônia (T.N.: Amazon Biotechnology Center) (CBA)), in Manaus/AM. The experiment was installed at the Laboratório de Cultura de Tecidos Vegetais/CBA (T.N.: Plant Tissue Culture Laboratory), where the explants were desinfected and grown in culture medium according to MURASHIGE e SKOOG (MS) and in Wood Plant Medium (WPM), during 60 days. The disinfestation rate obtained was 75% and, of the disinfested seeds, 100% germinated. The cultivation medium that was more favorable to the cultivation of simaba was the MS, where the multiplication rate was of 8.0: 1, whose seedlings reached, in average, 4.8 cm and 75% of rooting.
Acesso aberto (Open Access)
Processo de secagem de Morinda citrifolia L. em secador de radiação com lâmpadas refletoras, utilizando planejamento composto central rotacional
(Universidade Federal do Pará, 2015-10-16) BARROS, Hellen Carvalho; BRASIL, Davi do Socorro Barros; http://lattes.cnpq.br/0931007460545219; FARIA, Lênio José Guerreiro de; http://lattes.cnpq.br/7428609361678173
Morinda citrifolia Linn, popularly known as Noni, is a plant in the Rubiaceae, family that has been used for many centuries in popular medicine. The ancestors of the Polynesians discovered the plant and there have been numerous reports of its therapeutic and nutritional properties. For that reason, it was decided to carry out a study with the fruits of the species Morinda citrifolia L., in order to encourage use of the fruit for consumption in people’s diet, as well as to confirm its functional potential after drying. In this research, the conditions for drying Noni fruits were studied, and the phenolic compounds and antioxidant activity of the extracts obtained were assessed and quantified. In the drying process a dryer with reflecting lamps was used at the laboratory scale. In analyzing the process a statistical model was used as a basis, to quantify the effects of the entry variables in the Responses, by means of regression analyses through rotational central compound planning (PCCR) with two entry variables and five levels, employing temperature and size of the pulp as entry variables and final humidity level, antioxidant capacity and free radical sequestration activity as responses. It was observed that increasing the drying temperature led to a decrease in the final humidity level of Morinda citrifolia L fruits.The values of the responses observed varied from 0,01 a 3,50 bs, for drying; 1,32% a 38,8%, and 12,54 to 26,56(mg Eag/g) for phenolic levels.Within the experimental domain, only the variable of the isolated entry X1 (temperature) in the linear and quadratic forms were statistically influential on the Xbsresponse variable.
Acesso aberto (Open Access)
Recursos específicos e sua ativação para o desenvolvimento territorial: o caso da fitoterapia popular em Marapanim-PA
(Revistas Brasileiras Publicações de Periódicos e Editora Ltda., 2020-04) PINHEIRO, Ailton Castro; BARBOSA, Wagner Luiz Ramos; VASCONCELLOS SOBRINHO, Mário
The article aims to analyze the formation and activation of Specific Resources in the area of Popular Phytotherapy in the Paraense Amazon. For this, a participatory, documentary and bibliographic research was carried out focusing on the city of Marapanim-PA, which stands Brazilian Journal of Development Braz. J. of Develop., Curitiba, v. 6, n. 4,p.18022-18036 apr. 2020. ISSN 2525-8761 18023 out for having an association of women who for more than 20 years practices popular herbal medicine and for having approved, in 2019, its municipal program. of Medicinal Plants and Herbal Medicines. The result shows that the Specific Resource was the result of a long learning process where the partnership with the university was fundamental for the creation of appropriate technologies, such as social biotechnology, but the effective activation of this resource is still a challenge in this territory.
Acesso aberto (Open Access)
O uso da planta “pata–de–vaca” (Bauhinia Forficata) no tratamento do diabetes mellitus: um estudo na feira do Ver–o–Peso em Belém–Pará, Amazônia, Brasil
(Universidade Federal do Pará, 2021-12-14) SILVA, Bruna Leticia Rosário da; SILVA, Iracely Rodrigues da; http://lattes.cnpq.br/5393264898435715; OLIVEIRA, Euzébio de; http://lattes.cnpq.br/1807260041420782; https://orcid.org/0000-0001-8059-5902
The Ver–o–Peso fair, located in Belém do Pará, is considered the largest open market in Latin America. There, a large number of plant species with varied medicinal properties are for sale, being used by residents of the city of Belém and metropolitan region for the treatment of numerous diseases. Despite this, many plants have not yet been scientifically identified/registered or patented by the pharmaceutical industry for their various uses and medicinal properties, which have been used, often for centuries, through traditional knowledge and ways. This work aims to characterize the forms of therapeutic/medicinal uses of the plant species known as “pata-de-vaca” (Bauhinia Forficata), in the treatment of Diabetes Mellitus, in the urban region of Belém do Pará, also verifying what they are. the active principles of this plant species that influence its effectiveness for the treatment of this disease. The research has a qualitative methodological approach, carried out through field research, using as data collection instruments, the application of free listing, interviews with key informants, application of forms/questionnaires, direct observation, audio recording of respondents and photographic records of the studied plant. The results of this research show that the urban region of the city of Belém do Pará has a large framework of traditional knowledge about medicinal plants and is very familiar with the practices employed in the use of medicinal plants that are used for health care. With that, the conclusion of this work, which in this case the research focus was the Bauhinia Forficata, showed that this plant has great commercialization and revealed efficacy when used for the treatment of Diabetes Mellitus. The findings also contributed to the recognition and appreciation of local knowledge and practices on the "pata-de-vaca" (Bauhinia Forficata) that are present in the urban region, and are being applied/used for treatment and consequent promotion of quality of life of diabetic patients.
Acesso aberto (Open Access)
O uso de plantas medicinais no tratamento de leshimaniose tegumentar no município de São Domingos do Capim, Pará
(Universidade Federal do Pará, 2024-03-28) LEAL, Helen Betânia Lobato; OLIVEIRA, Euzébio de; http://lattes.cnpq.br/1807260041420782; https://orcid.org/0000-0001-8059-5902
Neglected Tropical Diseases (NTDs) refer to a group of diseases that mainly affect areas of extreme poverty. These often do not receive due attention and investment in research, prevention and treatment. The Northern region of Brazil is responsible for the largest number of reported cases, especially the municipality of São Domingos do Capim/PA. This motivated the need to understand which natural therapeutic means are used in the treatment of NTDs, especially Tegumentary Leishmaniasis (TL) in this municipality. This study aimed to evaluate the number of positive cases of the disease under study, during the last 5 years in the municipality, as well as to identify the use of medicinal plants that are most used for the treatment of TL in individuals with the disease. This is a descriptive, cross sectional and observational, qualitative study carried out based on the application of a questionnaire to assess the socioeconomic and structural conditions of the studied community. After information was provided by the Municipality's Health Surveillance sector, a total of 06 people were found positive for LT in the last 5 years. This study shows that the numbers of people reported as positive for LT in the Municipality of São Domingos do Capim between 2019 and 2023 are lower when compared to other municipalities in the northern region, despite this, Pará still remains in the ranking of one of the largest states that most notify LT in Brazil. Afterwards, it was noted that four people (04) reported not having used any medicinal plant as a therapeutic measure, and only two (02) people reported having used any medicinal plant at the beginning of the disease treatment, however they still reported that they did not they used it for more than a week, given that they did not obtain good results, and that in addition, the plants used contributed to the worsening of the symptoms. This study shows that despite the Municipality of São Domingos do Capim still having a precarious basic sanitation system, and high social vulnerability among other aggravating factors, LT had a significant drop in cases reported by the local Surveillance. It is important to mention that the majority of participants reported being very well supported by this sector, with appropriate drug treatments for the disease. Therefore, the use of medicinal plants as an alternative cure or treatment for this disease was considered scarce, with LT being considered a rarer practice in this study.
Acesso aberto (Open Access)
Uso de recursos naturais por seis comunidades ribeirinhas da Volta Grande do Xingu
(Universidade Federal do Pará, 2023-09-29) SOUZA, Thais Santos; SERRA , Anderson Borges; http://lattes.cnpq.br/9878285735905103; SANTOS, Graciliano Galdino Alves dos; http://lattes.cnpq.br/8085271321555747; HERNÁNDEZ-RUZ, Emil José; http://lattes.cnpq.br/9304799439158425
The Amazon basin has a potential for harnessing its water resources, which has been explored by building hydroelectric plants to meet the growing demand for energy generation. However, hydroelectric plants cause great transformations in the use of natural resources, such as fishing and the use of forest resources. This is the case of the construction of the Belo Monte hydroelectric plant (UHE) on the Xingu River, west of Pará. In the research, we studied what changes occurred in the use of medicinal plants, fishing, and hunting after the construction of the Belo Monte UHE, in six communities in region of Volta Grande do Xingu. 45 semi-structured interviews were carried out, with the application of tests with families who live next to the river after the construction of the Belo Monte HPP and who exercise or have already used flora, hunting and fishing activities, both for commercial purposes and for consumption. domestic. The frequency of use of each species for hunting, medicinal plants and fishing was observed. There was a reduction in species appreciated for consumption of fish and wild animals (game). In the use of medicinal plants, andiroba obtained the highest frequency of use. Thus, considering the results, that the use of medicinal plants in riverside families occurred after the construction of the Belo Monte HPP, for fishing and hunting there was a reduction of species appreciated for consumption, and consequently these factors provoke changes in the way of life of riverside families.