Artigos Científicos - EAUFPA

URI Permanente para esta coleçãohttps://repositorio.ufpa.br/handle/2011/9360

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Acesso aberto (Open Access)
Aspectos de gênero e vulnerabilidade ao HIV/AIDS entre usuários de dois dos serviços de atendimento especializado em DST/AIDS de São Luís, Maranhão
(Universidade Federal do Pará, 2016-09) MAFRA, Rogério Luís Pereira; PEREIRA, Ediléa Dutra; VARGA, István van Deursen; MAFRA, Welma Cristina Barbosa
We examine factors that contribute to the vulnerability of men and women living with HIV/AIDS, users of the Serviço de Atendimento Especializado em DST/AIDS (SAE), examining demographic and epidemiological differences as well as their reception and access to diagnosis and treatment. We conducted an observational, descriptive and cross-sectional study, in which 248 individuals were interviewed between October and December of 2007. We applied the chi-square test and multivariate analysis by CHAID technique (significance level of 5%). We established a classification by sex. We felt that some elements of an individual, programmatic and social level, including gender, contributed significantly to the vulnerability of the respondents. We observed substantial differences between men and women, considering: employment and income, total partners and condom use. The manner of shelter and access to diagnosis and treatment in the SAE is presented as an element of increased vulnerability, for not promoting a comprehensive service to the users. We identified aspects of differential vulnerability of women in the group over the "condom use after diagnosis", associated with the type of partnership (steady or not) and "understanding of what it is been saidduring the consultations", which was directly related to service time at SAE. In this sense, a way to reduce vulnerability pervades the pursuit of gender equity, ethnicity, to improve the quality of life.
Acesso aberto (Open Access)
Precipitation reaction of clavulanic acid: thermodynamic and electronic study
(Universidade Federal do Pará, 2016-09) MALPASS, Ana Claudia Granato; COSTA, Edson Barbosa da; ANGELOTTI, Wagner Fernando Delfino; MALPASS, Geoffroy Roger Pointer; BARBOZA, Marlei; SILVA, Albérico Borges Ferreira da; TRSIC, Milan
In the present article the theoretical calculation of thermodynamic parameters for the two main precipitation agents, potassium 2-ethylhexanoate and t-octylamine, employed by the pharmaceutical industry to obtain potassium clavulanate for clinical use, is described. The results obtained using the standard thermochemistry calculation in the Gaussian package and by calculation of the reactivity indexes of the reagents and products are compared. The calculated thermodynamic parameters indicate that the reactivity indexes present a better correlation with the experimentally obtained percentage yield. In addition, a series of additional precipitation agents that are also used in industrial procedures to obtain potassium clavulanate for clinical use, were compared. This was done to verify if any present, a priori, better properties than potassium 2-ethylhexanoate or t-octylamine. The consistency of the reactivity indexes calculated clearly suggests that the methodology employed can be used to screen future precipitation agents for possible use in the production of potassium clavulanate.

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