Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital

dc.creatorPIRES, Carla Andréa Avelar
dc.creatorNORONHA, Marcos Antônio Neves
dc.creatorMONTEIRO, Julius Caesar Mendes Soares
dc.creatorCOSTA, Albert Luiz Costa da
dc.creatorABREU JUNIOR, José Maria de Castro
dc.creator.Latteshttp://lattes.cnpq.br/4043070406676676pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/8100979196178150pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/4692404138975316pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/0910838783206481pt_BR
dc.creator.Latteshttp://lattes.cnpq.br/3888150171594943pt_BR
dc.date.accessioned2019-04-03T17:42:22Z
dc.date.available2019-04-03T17:42:22Z
dc.date.issued2018-08
dc.description.abstractBackground: Kaposi’s sarcoma (KS) is a rare neoplasm with indolent progression. Since 1981, the Kaposi’s sarcoma epidemic has increased as co-infection with HIV. Objectives: The study aimed to identify the clinical and demographic characteristics and therapeutic approaches in HIV/AIDS patients in a regional referral hospital. Methods: We analyzed the medical records of 51 patients with histopathological diagnosis of Kaposi’s sarcoma hospitalized at Hospital Universitário João de Barros Barreto (HUJBB) from 2004 to 2015. Results: The study sample consisted of individuals 15 to 44 years of age (80.4%), male (80.4%), single (86.3%), and residing in Greater Metropolitan Belém, Pará State, Brazil. The primary skin lesions identified at diagnosis were violaceous macules (45%) and violaceous papules (25%). Visceral involvement was seen in 62.7%, mainly affecting the stomach (75%). The most frequent treatment regimen was 2 NRTI + NNRTI, and 60.8% were referred to chemotherapy. Study limitations: We assumed that more patients had been admitted to hospital without histopathological confirmation or with pathology reports from other services, so that the current study probably underestimated the number of KS cases. Conclusion: Although the cutaneous manifestations in most of these patients were non-exuberant skin lesions like macules and papules, many already showed visceral involvement. Meticulous screening of these patients is thus mandatory, even if the skin lesions are subtle and localized.pt_BR
dc.description.affiliationUFPA - Universidade Federal do Parápt_BR
dc.identifier.citationPIRES, Carla Andréa Avelar et al. Kaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospital. Anais Brasileiros de Dermatologia, Rio de Janeiro, v. 93, n. 4, p. 524-528, ago 2018. Disponível em: http://repositorio.ufpa.br/jspui/handle/2011/10862. Acesso em:.pt_BR
dc.identifier.doihttp://dx.doi.org/10.1590/abd1806-4841.20186978pt_BR
dc.identifier.issn1806-4841pt_BR
dc.identifier.urihttps://repositorio.ufpa.br/handle/2011/10862
dc.languageengpt_BR
dc.publisherUniversidade Federal do Parápt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.initialsUFPApt_BR
dc.relation.ispartofAnais Brasileiros de Dermatologiapt_BR
dc.rightsAcesso Abertopt_BR
dc.source.urihttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000400005&lng=pt&nrm=isopt_BR
dc.subjectAcquired immunodeficiency syndromept_BR
dc.subjectHIVpt_BR
dc.subjectHuman herpesvirus 8pt_BR
dc.subjectKaposi’s sarcomapt_BR
dc.titleKaposi’s sarcoma in persons living with HIV/AIDS: a case series in a tertiary referral hospitalpt_BR
dc.typeArtigo de Periódicopt_BR

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