Prevalência de HPV em material cérvico-uterino de mulheres de Tomé-Açú – PA

Abstract

The human papillomavirus (HPV) infects basal of stratified epithelium and develop proliferative benign lesions in skin or mucous. The infection has a universal distribution however many studies have demonstrated a strong association of infections by high risk species in cases of cervical cancer. In Brazil, this type of cancer is the second most common among women, while the north and northeast region of this country have the highest incidence. Therefore, this study has as focus the determination of infection prevalence in a group of women screened to cervical cancer. During the period of July 2008 to March 2009 were collected cervical samples from 144 women received at Laboratório de Citopatologia of Hospital Amazônia from Quatro Bocas, Tomé-Açú, Pará. All women were informed about the purpose of that research and then signed the Consent Form and answered the epidemiological questionnaire. The data obtained from the questionnaire correlated with the infection through the testing qui -quadradot. The HPV prevalence was 6,94% and the majority age was between 18-28 years. Samples from 76 patients showed inflammatory aspect (52,02%) and 60 patients did not showed any change (41,09%). Among smears with cytological ASC-US in the most of cases (6/10) followed by LSIL (2/10), and ASC-H (1/10) and HSIL (1/10). The HPV infection is statistically significant correlated PCR-HPV test with the age group, and cytomorphology. Prevalence found in this study corroborants with other findings reported in the literature. The predominance of infection in women with abnormal cytology strengthens the concept that infection is, in most of cases, asymptomatic, and the Pap smear method is lesser efficient to detect infection than techniques of molecular biolology.